A fatal case of potassium dichromate ingestion is documented. A retrospective review of serum and organ levels of chromium demonstrates that charcoal haemoperfusion, peritoneal and haemodialysis are ineffective therapies for the toxin. Other treatments for this poisoning are reviewed, the poor prognosis of dichromate ingestion, and the paucity of effective therapy underlined. The application of dichromates in traditional medications is briefly discussed; this is a toxin which may be more prevalent than previously thought. It is proposed that the exposure limits of dichromate be more widely publicised.
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Article Synopsis
- * A study on SD rats revealed that Cr(VI) exposure led to increased lung damage, apoptosis in lung cells, and alterations in various blood and urine metal levels, which suggest significant biochemical changes.
- * After stopping Cr(VI) exposure, some damage showed improvement, indicating potential for recovery, but oxidative stress in lung tissues remained disrupted even after 14 days of cessation.
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