Amphibian embryos have served as a model system for vertebrate axial patterning for more than a century. Recent changes to the Xenopus laevis fate map revised the assignment of the embryonic dorsal/ventral (back-to-belly) axis in pre-gastrula embryos and allowed the assignment of the rostral/caudal (head-to-tail) axis for the first time. Revising the embryonic axes after many years of experimentation changes our view of axial patterning in amphibians. In this review, we discuss the revised maps and axes, and show by example how the new map alters the interpretation of three experiments that form the foundations of amphibian embryology. We compare the revised amphibian fate map to the general maps of the protochordates, and discuss which features of the maps and early development are shared by chordates and which distinguish vertebrates. Finally, we offer an explanation for the formation of both complete and incomplete axes in the rescue assays routinely used to study axial patterning in Xenopus, and a model of amphibian axial patterning.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.ydbio.2006.04.447 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Perceived effects of health status on sexual activity in patients with axial spondyloarthritis: a 5-year follow-up study.
Rheumatol Int
December 2024
Division of Rheumatology, Department of Internal Medicine, Sorlandet Hospital, Kristiansand, Norway.
Axial spondyloarthritis (ax-SpA) causes pain, fatigue, stiffness, loss of physical function, and poor health status, which can influence sexual activity and enjoyment. To explore whether patients with ax-SpA perceive that their health status effects their sexual activity and to identify predictors of these perceived effects on sexual activity after a 5-year follow-up. Data about demographics, disease, medication, health-related quality of life (HRQOL), and sexual quality of life (SQOL) were collected at the baseline and 5-year follow-up.
View Article and Find Full Text PDFFactors associated with patients' demand for low-value care: a scoping review.
BMC Health Serv Res
December 2024
Department of Health Economics and Health Services Research, National Institute for Public Health and the Environment (RIVM), P.O. Box 13720, Antonie van Leewenhoeklaan 9, Bilthoven, BA, Netherlands.
Background: Low-value care is unnecessary care that contributes to inefficient use of health resources and constitutes a considerable proportion of healthcare expenditures worldwide. Factors contributing to patients' demand for low-value care have often been overlooked and are dispersed in the literature. Therefore, the current study aimed to systematically summarize factors associated with patients' demand for low-value care.
View Article and Find Full Text PDFThe time-course changes in postural control variability between neck pain and asymptomatic dental students.
Sci Rep
December 2024
Neuromuscular Research Lab, Interdisciplinary Centre for the study of Human Performance (CIPER), Faculty of Human Kinetics, University of Lisbon, 1499-002, Oeiras, Portugal.
Changes in postural control associated with clinical practice or specific conditions such as the presence of neck pain remain unexplored in dental students. Therefore, this study aimed to explore the time-course changes in postural control complexity among dental students enrolled in clinical practice, comparing those with and without neck pain. We used an online Nordic Musculoskeletal Questionnaire for group allocation and center of pressure (CoP) oscillations with a tri-axial Bertec force plate.
View Article and Find Full Text PDFHindlimb locomotor biomechanics of the derived therizinosaur Nothronychus: Functional changes in the line to birds and convergence with large-bodied neornitheans.
Anat Rec (Hoboken)
December 2024
Biology Department, Northland Pioneer College, Holbrook, Arizona, USA.
Nothronychus graffami was a large therizinosaur represented by a single well-preserved individual from the Turonian Tropic Shale of southern Utah. It is characterized by an enlarged abdomen, small tail, and an extensively pneumatized axial skeleton, and is frequently regarded as herbivorous. Given the overall tail reduction and the development of a wide fused synsacrum with widely spaced acetabulae, it is reconstructed with an anteriorly rotated femur and a displaced resting ground reaction force anterior to the center of mass.
View Article and Find Full Text PDFCorporal punishment (CP) is a widely extended practice within Ecuadorian households. However, there is international pressure to ban it, CP is not considered a topic of relevance either for researchers nor public policy, and there is a lack of information about this phenomenon, its causes, and effects in this specific context. That is why this research aims to identify common beliefs supporting CP usage inside homes since beliefs have been found to shape individual behavior at the same time they are socially and culturally produced.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!