A 35-year-old man with systemic non-Hodgkin's lymphoma and bilateral choroidal involvement is described. Indocyanine green angiography depicts choroidal involvement much better than fluorescein angiography and seems to be superior in diagnosing and monitoring patients with systemic non-Hodgkin's lymphoma and choroidal involvement.
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http://dx.doi.org/10.3928/15428877-20060501-10 | DOI Listing |
Alzheimers Dement
December 2024
Alzheimer Center Limburg, School for Mental Health and Neuroscience, Maastricht University, Maastricht, Netherlands.
Background: Structural and functional changes of the choroid plexus (ChP) have been reported in Alzheimer's disease (AD). Nonetheless, the role of the ChP in the pathogenesis of AD remains largely unknown. We aim to unravel the relationship between ChP functioning and core AD pathogenesis using a unique proteomic approach in mice and humans.
View Article and Find Full Text PDFCureus
December 2024
Department of Ophthalmology, Xi'an No. 3 Hospital, the Affiliated Hospital of Northwest University, Xi'an, CHN.
Choroidal nevus is the most common intraocular tumor, and most cases are benign and have no symptoms. However, choroidal nevus carries a low risk for transformation into melanoma, which is a highly aggressive and deadly cancer. In this case report, we present a male patient with blurred vision in his left eye for six months.
View Article and Find Full Text PDFSci Rep
January 2025
The Department of Ophthalmology, General Hospital of Central Theater Command, No. 627 Wuluo Road, Wuchang District, Wuhan, 430000, Hubei, China.
This study used ultra-widefield swept-source optical coherence tomography angiography (UWF SS-OCTA) to analyze and compare choroidal blood flow and anatomical changes in eyes affected by central serous chorioretinopathy (CSC), pachychoroid neovasculopathy (PNV), and uncomplicated pachychoroid (UCP). The findings revealed distribution patterns of vortex veins across the three patient groups and provided initial findings insights into the origin of choroidal neovascularization (CNV) in PNV. A total of 44 patients with CSC, 38 with PNV, and 46 with UCP were included in the analysis.
View Article and Find Full Text PDFMol Cell Endocrinol
December 2024
Amsterdam Institute for Life and Environment (A-Life), Vrije Universiteit Amsterdam (VU), De Boelelaan 1085, 1081 HV Amsterdam, The Netherlands.
Adequate levels of thyroid hormones (THs) in the fetal brain are vital for early neurodevelopment. Most of TH in fetal brain is derived from circulating thyroxine (T4), which gets locally converted into the biologically active triiodothyronine (T3) by deiodinase enzymes. One of the major routes of TH into the brain is through the blood-cerebrospinal fluid barrier (BCSFB).
View Article and Find Full Text PDFGraefes Arch Clin Exp Ophthalmol
December 2024
Department of Pediatric Retina & Ocular Oncology, Aravind Eye Hospital & Postgraduate Institute of Ophthalmology, Avinashi Road, Coimbatore, 641 014, Tamil Nadu, India.
Background: To describe the spectrum, demographic profile and distribution of intraocular oncology cases; both benign and malignant, in pediatric population in India.
Methods: It was a retrospective study done at a tertiary care hospital over a period of seven years (January 2015- December 2022) which included all the children aged 0-16 years, clinically diagnosed as intraocular tumors (benign or malignant) referred to our Ocular Oncology clinic. The data was retrieved from medical records department as well as electronic medical system (EMR) system.
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