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Lotilaner for Demodex Blepharitis: The Journey from Veterinary Use to Human Medicine.
J Ocul Pharmacol Ther
March 2025
Department of Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
In 2023, Xdemvy® (0.25% lotilaner ophthalmic solution) was approved by the U.S.
View Article and Find Full Text PDFCausing Necrotizing Fasciitis in a Patient of Autoimmune Myelofibrosis and Type 2 Diabetes: A Rare Case Report.
J Assoc Physicians India
January 2025
DNB Trainee, Department of Internal Medicine, Sir Ganga Ram Hospital, New Delhi, India.
Demodicosis is a skin disease caused by the Demodex mite. It commonly involves areas in or near pilosebaceous units. Infestation with Demodex is asymptomatic but may have a pathogenic role in immunocompromised individuals or when present in high densities.
View Article and Find Full Text PDFIntroduction: Lotilaner ophthalmic solution (0.25%) is the first United States Food and Drug Administration (US FDA)-approved drug for treating Demodex blepharitis. In pivotal trials, it was found to be well tolerated and demonstrated a significant reduction in collarettes and mite density after a 6-week treatment regimen.
View Article and Find Full Text PDFKnowledge, Attitude, Awareness, and Practice Regarding Mites Among the Thai Population.
Patient Prefer Adherence
January 2025
Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Background: mites are common ectoparasites in humans and can cause various skin disorders known as demodicosis, ranging from nonspecific facial dermatitis to conditions resembling eczema, seborrheic dermatitis, folliculitis, and acne. Overgrowth of these mites can lead to pityriasis folliculorum, perioral dermatitis, blepharitis, and rosacea, significantly impacting skin health. This study aims to investigate the knowledge, attitude, awareness, and practice regarding mites in the Thai population and analyze the influencing factors associated with these aspects.
View Article and Find Full Text PDFPrevalence and Severity of and Infestation and Their Association with Common Skin Diseases in Northwest Iran.
J Arthropod Borne Dis
June 2024
Department of Parasitology, Van Yuzuncu Yil University Faculty of Medicine, Van, Turkey.
Background: spp., a cosmopolitan mite, can exist as a commensal or parasitic organism. This study aimed to investigate the prevalence of spp.
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