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Postpartum Remote Health Coaching Intervention for Individuals With a Hypertensive Disorder of Pregnancy: Proof-of-Concept Study.
JMIR Form Res
January 2025
Department of Health and Human Physiology, University of Iowa, Iowa City, IA, United States.
Background: Cardiovascular disease (CVD) is the leading cause of death among women in America. Hypertensive disorders of pregnancy (HDP) negatively impact acute and long-term cardiovascular health, with approximately 16% of all pregnancies affected. With CVD 2-4 times more likely after HDP compared to normotensive pregnancies, effective interventions to promote cardiovascular health are imperative.
View Article and Find Full Text PDFBenefits of physical exercise through multivariate analysis in sedentary adults and elderly: An analysis of physical fitness, health and anthropometrics.
Exp Gerontol
January 2025
School of Physical Education of Ribeirão Preto, University of São Paulo, Ribeirão Preto, Brazil.
This study employed multivariate analysis to investigate the effects of a 14-week multicomponent training program on sedentary adults and older populations, focusing on improvements in physical fitness, health markers, and anthropometric measures. The data included 376 participants aged 30 to 84 years who had been inactive for at least 3 months. Results showed that participants aged 71 and above had lower systolic blood pressure, height, body mass, elbow flexion and extension, sitting and standing up from a chair, agility, 6-Minute Walk Test (6MWT), and handgrip strength values compared to younger age groups (p < 0.
View Article and Find Full Text PDFClinical and cost-effectiveness of parenting intervention for mothers experiencing psychosocial stress: insights from the early closure of the Mellow Babies RCT.
Public Health Res (Southampt)
December 2024
Edinburgh Clinical Trials Unit, Usher Institute, University of Edinburgh, Edinburgh, UK.
Background: Problems in children's early social and emotional development are likely to have major long-term consequences for the individual and society: maternal emotional well-being is associated with better outcomes. Interventions designed to improve both maternal mental health and the mother-child relationship are thus likely to benefit both maternal health and child development.
Objectives: To establish the clinical and cost-effectiveness of the Mellow Babies parenting intervention for women experiencing psychosocial stress and their 6- to 18-month-old babies.
Impact of combined exercise on blood DNA methylation and physical health in older women with obesity.
PLoS One
December 2024
Research Division, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand.
This study examined the effects of a 14-week combined exercise program on blood DNA methylation (DNAm) and its potential biological pathways in normal-weight, overweight, and obese older women. A total of 41 participants were assessed at baseline, 7 weeks, and 14 weeks into the training. Their whole-blood DNAm profiles were measured using the Infinitum MethylationEPIC BeadChip, alongside physical and biochemical health evaluations.
View Article and Find Full Text PDFBenzo[]pyrene and phenanthrene hemoglobin adducts as biomarkers of longer-term air pollution exposure.
Environ Sci Process Impacts
November 2024
Nicholas School of the Environment, Duke University, 308 Research Drive, LSRC Room A309, Durham, NC 27708, NC, USA.
Article Synopsis
- The study examines PAH-hemoglobin adducts in blood samples from pregnant women in Rochester, NY, as potential long-term exposure biomarkers for air pollution.
- Researchers measured specific hydrolysis products of PAH-hemoglobin adducts (BaPT and PHET) and linked these to cumulative exposure to particulate matter (PM) during pregnancy.
- The results indicated positive correlations between these biomarker levels and PM exposure over specified gestational weeks, highlighting PAH-hemoglobin adducts as effective indicators of longer-term air pollution exposure, while no link was found with NO exposure.
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