Are branched chain fatty acids the natural substrates for P450(BM3)?

Chem Commun (Camb)

Department of Chemistry, University of Queensland, St. Lucia, Brisbane, Australia 4072.

Published: June 2006

Branched chain fatty acids are substrates for cytochrome P450(BM3) (CYP102) from Bacillus megaterium; oxidation of C15 and C17 iso and anteiso fatty acids by P450(BM3) leads to the formation of hydroxylated products that possess high levels of regiochemical and stereochemical purity.

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http://dx.doi.org/10.1039/b601202gDOI Listing

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