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Endoscopic ultrasound-guided biliary drainage (EUS-BD) might be an alternative to percutaneous or transpapillary biliary drainage in unresectable pancreatic or biliary cancer. A lumen-apposing, fully covered, self-expanding metal stent, which creates a sealed transluminal conduit between the biliary and gastrointestinal tract may offer advantages over conventional plastic and metal stents. In this retrospective, observational, open-label case study, five patients underwent EUS-BD for obstructive jaundice in pancreatic cancer (n = 4) or distal cholangiocarcinoma (n = 1).

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Endoscopic ultrasound-guided bilio-pancreatic drainage (EBPD) has become an endoscopic alternative to percutaneous biliary drainage for patients with unsuccessful transpapillary approach. EBPD has a significant complication rate and expertise in advanced therapeutical endoscopy and endosonography are required. We present a 43 year-old male with pancreatic head adenocarcinoma, who after underwent a transgastric endoscopic rendez-vous technique, a gastric wall perforation at the fistula location was detected.

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Background: Pancreatic necrosis and pancreatic abscess are severe complications of acute pancreatitis. Surgery is associated with significant morbidity and mortality in these critically ill patients. Endoscopic therapy has the potential to offer a safer and more effective alternative treatment modality.

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