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Lessons learned from a case of placenta previa totalis complicated by placenta accreta spectrum: Importance of timely decision-making.
Int J Surg Case Rep
December 2024
Department of Obstetrics and Gynecology, Tishreen University, Lattakia, Syria.
Introduction And Clinical Importance: Placenta previa (PP) is characterized by abnormal placental placement in the lower uterine segment, obstructing the cervical opening. Placenta previa totalis (PPT) occurs when the placenta completely covers the internal cervical os. This condition can lead to placenta accreta spectrum (PAS), where the placenta adheres abnormally to the uterine wall, complicating separation.
View Article and Find Full Text PDFManagement of a young HoFH patient during pregnancy using Lipoprotein Apheresis (whole blood): A novel experience.
Transfus Apher Sci
December 2024
Department of Maternal and Child Health and Urological Sciences, Umberto I Hospital, "Sapienza" University of Rome, Viale del Policlinico 155, Rome 00161, Italy. Electronic address:
The pregnancy of a patient with homozygous familial hypercholesterolemia (HoFH) represents a challenge in the clinical setting due to the high cardiovascular risk of the mother and maternal-fetal morbidity. The lipid lowering drugs are generally contraindicated and lipoprotein apheresis (LA) is the only accepted treatment in HoFH pregnant woman. Liposorber D, an LA technique on whole blood, has good efficacy, safety, and short operative time.
View Article and Find Full Text PDFSelective termination: a life-saving procedure for complicated monochorionic gestations.
J Perinat Med
December 2024
Fetal Care and Surgery Center (FCSC), Division of Fetal Medicine and Surgery, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
Monochorionic twin pregnancies are a subset of twin pregnancies that face potential complications related to a shared circulation between the fetuses. These complications are related to anastomotic placental vessels connecting the cardiovascular systems of the two fetuses, which can result in significant sequela if one twin experiences intrauterine death. The sudden cardiovascular collapse in this scenario leads to a massive blood shift away from the healthy co-twin, significantly jeopardizing its life and long-term neurodevelopmental outcome.
View Article and Find Full Text PDF[Genetic analysis of two novel variants in a Chinese pedigree affected with intellectual disorder].
Zhonghua Yi Xue Yi Chuan Xue Za Zhi
December 2024
Key Laboratory of Precision Medicine and Testing of Wenzhou City, Clinical Laboratory of Wenzhou Central Hospital, Wenzhou, Zhejiang 325000, China.
Objective: To explore the clinical phenotype and genetic characteristics of two siblings with intellectual disability.
Methods: Clinical data and peripheral blood samples were collected from the proband, his younger sister and parents whom had presented at Wenzhou Central Hospital in February 2024. Low-coverage massively parallel copy number variation sequencing (CNV-seq) and whole exome sequencing (WES) were carried out for the family.
Diagnosis and management challenges of recurrent lupus pericarditis in pregnancy: A case report.
Case Rep Womens Health
December 2024
Department of Obstetrics and Gynecology, Faculty of Medicine, Airlangga University, Dr. Soetomo General Academic Hospital, Surabaya, Indonesia.
Systemic lupus erythematosus (SLE) is an autoimmune multisystem disease. Pericarditis in SLE can lead to severe effusion and cardiac tamponade, and is associated with significant morbidity and mortality. Therefore, early diagnosis and treatment are essential.
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