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The Effect of Sex Hormones on Joint Ligament Properties: A Systematic Review and Meta-analysis.
Am J Sports Med
January 2025
Department of Orthopaedic Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Background: Sex differences exist in injury rates, and one contributing factor may be sex hormone effects on the musculoskeletal system.
Purpose/hypothesis: The goal of this systematic review and meta-analysis was to understand the effects of sex hormones on ligaments in females as determined by preclinical and clinical studies. The hypothesis was that sex hormones would affect ligament mechanical properties, histological features, cellular function, and clinically measurable outcomes.
Vascular health and exercise in females throughout the lifespan: Exploring puberty, pregnancy and menopause.
Exp Physiol
January 2025
Department of Exercise Science and Health Promotion, Florida Atlantic University, Boca Raton, Florida, USA.
This narrative review highlights the impact of exercise on vascular health in females over the lifespan with an emphasis on puberty, pregnancy and menopause. These events encompass substantial changes in sex hormone levels, particularly oestrogens and progesterone. They are also accompanied by distinct adaptations of the central, peripheral and cerebral vasculature.
View Article and Find Full Text PDFImpact of Successive Sets of High-Intensity Leg Press on Cerebral Hemodynamics Across Menstrual Cycle Phases.
Am J Physiol Regul Integr Comp Physiol
January 2025
Department of Kinesiology, Faculty of Science, McMaster University, Hamilton, ON, Canada.
This study examined how successive sets of high-intensity leg press (LP) resistance exercise impact the cerebral pressure-flow relationship in untrained males and eumenorrheic females not taking oral contraceptives, and assessed how menstrual cycle (MC) phase influences the cerebral pressure-flow relationship and cerebral hemodynamics (middle cerebral artery blood velocity; MCAv; via transcranial Doppler ultrasound) during and after LP exercise in females. Young adults (11M;11F) performed three sets of leg-press exercises at 90% of their 1-repetition maximum. Data from males and females in early follicular phase were pooled together.
View Article and Find Full Text PDFAssessment of Quadriceps Muscle Strength and Thickness in Adolescents with Polycystic Ovary Syndrome: A Case-control and Longitudinal Follow-up Study.
J Clin Res Pediatr Endocrinol
January 2025
Division of Adolescent Medicine, Department of Pediatrics, Faculty of Medicine, Hacettepe University, Ankara, Turkey.
Objective: No studies have investigated muscle strength and thickness in adolescents with polycystic ovary syndrome (PCOS). We investigated whether there were changes in quadriceps muscle thickness and strength between adolescents with PCOS and controls. Secondly, we evaluated the effects of six months of combined oral contraceptive (COC) treatment on the quadriceps muscle.
View Article and Find Full Text PDFAnamnesis Checklist for Informed Oral Contraceptive Choices: A Spanish Perspective.
Womens Health Rep (New Rochelle)
January 2025
Hospital Nuestra Señora de Fátima, Vithas Vigo, Vigo, Spain.
Objectives: This study aimed to develop an anamnesis checklist for oral contraceptive (OC) choice focused on their safety profile and associated risk factors.
Study Design: This study involved eight health care professionals in Spain, including six gynecologists and two internists, selected for their expertise in contraception counseling. We employed the design-thinking process, structured in five phases: empathizing with patients' needs, defining key areas of impact, devising innovative solutions, prototyping ideas into testable proposals, and validating prototypes.
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