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Elevation in compartment pressure following hypovolemic shock and fluid resuscitation: a canine model. | LitMetric

AI Article Synopsis

  • Researchers induced hemorrhagic shock in seven dogs and monitored their leg compartment pressures during bleeding and resuscitation with IV lactated ringers.
  • Compartment pressures in the resuscitated dogs were significantly higher than those in control dogs who did not experience bleeding.
  • The study suggests that while the increased pressures may not cause compartment syndrome outright, they highlight a greater risk for this condition in limbs that have gone through ischemia and reperfusion.

Article Abstract

We induced hemorrhagic shock in seven dogs and then resuscitated them with intravenous (IV) lactated ringers. We then monitored anterior leg compartment pressures via a slit catheter during both bleeding and reperfusion. These values were compared with controls that received IV fluids without being bled. Compartment pressures in resuscitated dogs rose well above control values. These values were statistically significant when compared to controls via the paired student t test (P < .01). This model demonstrates that sufficient swelling occurs to significantly elevate compartment pressures, even in the absence of local trauma. While this elevation may not be sufficient enough to cause a compartment syndrome, it reinforces the notion that extremities that have experienced ischemia and reperfusion are at an increased risk for developing compartment syndrome.

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Source
http://dx.doi.org/10.3928/01477447-20060501-07DOI Listing

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