Tiamulin, a new antibiotic for eliminating mycoplasmas from bovine serum 1. Investigations on Spermatozoal Toxicity.

Tiamulin, a new diterpene antibiotic, was investigated for toxicity to spermatozoa. The compound was added to ejaculates via semen extender at a concentration of 50 to 90 mg per 100 ml of total liquid. Motility and the proportion of non-viable spermatozoa were used as criteria of the drug's effect. Tiamulin proved to be safe up to doses of 70 mg per 100 ml of semen extender.