We have found a high incidence (4.8%) of allergy to hydrocortisone in patients with suspected allergic contact dermatitis. In view of this finding we would suggest that, in any condition that does not improve or that deteriorates after administration of hydrocortisone, allergy to this compound should be considered.
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http://dx.doi.org/10.1016/0140-6736(91)91373-3 | DOI Listing |
Am J Dermatopathol
December 2024
Department of Medicine, MacKay Medical College, New Taipei City, Taiwan; and.
Disseminated hypopigmented keratosis is a rare distinct clinical entity. This report describes the case of a 19-year-old male patient who developed disseminated hypopigmented keratosis 2 months after autologous hematopoietic stem cell transplantation for pineal choriocarcinoma. The patient displayed numerous tiny whitish or depigmented macules and papules on the chest, back, posterior neck, shoulders, arms, and thighs, closely resembling lichen nitidus.
View Article and Find Full Text PDFImmun Inflamm Dis
November 2024
Department of Clinical Pharmacy, Faculty of Pharmacy, Tanta University, Tanta, Al-Gharbia, Egypt.
Introduction: Atopic dermatitis (AD) is a type of chronic inflammatory disorder that affects all age groups including children. AD is characterized by elevated inflammatory marker levels.
Aim: To assess the safety and effectiveness of topical tacrolimus ointment versus topical hydrocortisone cream in the treatment of pediatric AD by comparing the two treatments' ability to reduce serum cytokines.
Cureus
September 2024
Internal Medicine, Centro Hospitalar Universitário do Algarve, Unidade de Portimão, Portimão, PRT.
Cureus
September 2024
College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, SAU.
Transplacental transmission of spirochetes from an infected mother to the fetus during pregnancy results in the infectious condition known as congenital syphilis (CS). Once a forgotten disease, CS has now re-emerged. We report the clinical case of an early CS in a neonate girl presented with severe congenital pneumonia (pneumonia alba) requiring intubation, along with skin lesions that were visible from birth on the palms and soles of the feet.
View Article and Find Full Text PDFBiomater Adv
January 2025
Department of Pharmacy, LEO Foundation Center for Cutaneous Drug Delivery, University of Copenhagen, Copenhagen, Denmark. Electronic address:
In this proof-of-concept study, we aimed to develop an anti-inflammatory patch that in contrast to the semi-solid standard therapy is dry and non-greasy, and only needs to be changed once a day due to continuous release of the active ingredient over 24 h. While fiber materials for the treatment of inflammatory skin diseases have been reported in the literature, the majority of studies focuses solely on material characterization including in vitro release studies; however, there is a lack of ex vivo permeation studies as well as comparison with standard therapy. However, such experiments are crucial to deduct the potential efficacy of the drug delivery system, as skin absorption of the drug may be the rate-limiting step and not the drug release.
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