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Demarcated Nonpruritic Lesions Following Antibiotic Therapy.
Cutis
December 2024
Olivia Humpel is from Lake Erie College of Osteopathic Medicine, Bradenton, Florida. Dr. Hostoffer is from Allergy/Immunology Associates Inc, Mayfield Heights, Ohio.
Safety of Cefazolin Perioperative Prophylaxis in Plastic Surgery Patients With Penicillin Allergy: A Retrospective Chart Review.
Plast Surg (Oakv)
February 2025
Division of Allergy and Immunology, The Ohio State University Wexner Medical Center, Columbus, OH, USA.
Antimicrobial prophylaxis is crucial in reducing surgical site infections (SSIs). First-generation cephalosporins are commonly first line, but issues arise when patients report a penicillin allergy. Although up to 10% of Americans report a penicillin allergy, up to 95% are not truly allergic.
View Article and Find Full Text PDFThe Global Prevalence of Reported Penicillin Allergy: A Systematic Review and Meta-Analysis.
J Infect
January 2025
Department of Infectious diseases- Faculty of Medicine, Imperial College London.
Objectives: Patients labelled with penicillin allergy (PenA) often receive broader spectrum antibiotics, associated with antimicrobial resistance and poorer outcomes. However, ~95% of patients are likely mis-labelled. Whilst de-labelling programmes are gaining momentum, they have been restricted to a few countries.
View Article and Find Full Text PDFEULAR recommendations for the treatment of systemic sclerosis: 2023 update.
Ann Rheum Dis
January 2025
Department of Rheumatology, Université Paris Cité UFR de Médecine, Paris, France.
Objectives: To update the 2017 European Alliance of Associations for Rheumatology (EULAR) recommendations for treatment of systemic sclerosis (SSc), incorporating new evidence and therapies.
Methods: An international task force was convened in line with EULAR standard operating procedures. A nominal group technique exercise was performed in two rounds to define questions underpinning a subsequent systematic literature review.
Penicillin allergy as an instrumental variable for estimating antibiotic effects on resistance.
Nat Commun
January 2025
Department of Epidemiology and Preventive Medicine, School of Public Health, Faculty of Medical & Health Sciences Tel Aviv University, Tel Aviv, Israel.
Antibiotic resistance is influenced by prior antibiotic use, but precise causal estimates are limited. This study uses penicillin allergy as an instrumental variable (IV) to estimate the causal effect of antibiotics on resistance. A retrospective cohort of 36,351 individuals with E.
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