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Polysomnographic Phenotype of Positional Obstructive Sleep Apnea.

J Rhinol

November 2024

Department of Otorhinolaryngology-Head and Neck Surgery, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.

Background And Objectives: Obstructive sleep apnea (OSA) is a prevalent sleep disorder characterized by recurrent upper airway obstruction, leading to disrupted sleep and various health complications. Positional OSA (POSA) refers to patients whose OSA severity is significantly influenced by body position, especially when lying supine. This study aimed to evaluate the polysomnographic characteristics of POSA and non-positional OSA (non-POSA) and to assess their clinical implications.

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Article Synopsis
  • The study examines the prevalence and characteristics of positional obstructive sleep apnea (POSA) in children with obstructive sleep apnea (OSA), analyzing 1,236 pediatric patients.
  • After filtering, 153 POSA and 306 non-positional OSA (NPOSA) patients were compared, revealing that POSA had a prevalence of 12.8%.
  • Results indicated that POSA patients had lower overall apnea-hypopnea indices (AHI), shorter total sleep time, and spent more time in non-supine sleep positions, suggesting that changes in sleep position could help reduce apnea occurrences in children.
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Article Synopsis
  • This study investigates how different characteristics of patients with obstructive sleep apnea (OSA) can predict their response to mandibular advancement devices (MAD) and aims to create a model for treatment efficacy.
  • It analyzed 112 patients over six years, categorizing OSA into different phenotypes, with findings indicating that positional-OSA patients had a significantly higher response rate to MAD compared to non-positional patients.
  • The results suggest that specific phenotypes, particularly REM-OSA, are less responsive to MAD treatment, highlighting key metrics like hypoxic burden and T90% that are useful in predicting treatment success in OSA patients.
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Purpose: Among the treatment options for Obstructive Sleep Apnea (OSA), intrapharyngeal surgery has undergone significant changes and received solid scientific support. However, it is crucial to identify the best candidate. This study aims to present the results of the modified Alianza technique in our clinic to show the differences in the impact of surgery on supine and non-supine apnea levels in moderate-severe OSA patients.

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Objective: To assess the surgical outcomes and identify predictors of surgical success in patients with positional and non-positional obstructive sleep apnea following multilevel airway surgery.

Study Design: Retrospective cohort study.

Setting: Singe-tertiary medical center.

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