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Alzheimers Dement
December 2024
Penn FTD Center, University of Pennsylvania, Philadelphia, PA, USA.
Background: Neuropsychiatric symptoms (NPS) including depression and apathy, are common in dementia and profoundly affect both patients and caregivers. These symptoms can manifest early and can be indicative of the disease progression. The existing tools for measuring NPS lack objectivity and are not sensitive enough to detect subtle changes in the earlier stages of dementia.
View Article and Find Full Text PDFDendrimers, Dendrons, and the Dendritic State: Reflection on the Last Decade with Expected New Roles in Pharma, Medicine, and the Life Sciences.
Pharmaceutics
November 2024
The National Dendrimer & Nanotechnology Center, NanoSynthons LLC, Mt. Pleasant, MI 48858, USA.
This perspective begins with an overview of the major impact that the dendron, dendrimer, and dendritic state (DDDS) discovery has made on traditional polymer science. The entire DDDS technology is underpinned by an unprecedented new polymerization strategy referred to as step-growth, amplification-controlled polymerization (SGACP). This new SGACP paradigm allows for routine polymerization of common monomers and organic materials into precise monodispersed, dendritic macromolecules (i.
View Article and Find Full Text PDFGenerational Differences in Self-Esteem and Vocal Perception Among Brazilian Gay Men.
J Voice
January 2025
Speech-Language Pathology Department, Universidade Federal de São Paulo - UNIFESP, Rua Botucatu, 802 Vila Clementino, 04023-062, São Paulo, São Paulo, Brazil. Electronic address:
Introduction: Self-esteem and vocal perception are central aspects of identity and self-presentation, particularly within marginalized communities where voice and self-concept can be deeply intertwined with social acceptance and cultural dynamics. Among Brazilian gay men, generational differences in these areas may reflect broader social changes, shifts in stigma, and evolving notions of masculinity. This study aims to explore these differences, examining how self-esteem and self-assessed vocal descriptions vary across generations, thereby shedding light on specific needs and areas for potential support within these communities.
View Article and Find Full Text PDFExperiences of Nursing Interns in the Neonatal Intensive Care Unit in Saudi Arabia: A Phenomenological Study.
Cureus
December 2024
Neonatal Intensive Care Nursing Program, Nursing Department, Fakeeh College for Medical Sciences, Jeddah, SAU.
Background: Clinical training in the neonatal intensive care unit (NICU) is a unique experience due to the specialty and complex care provided for critically ill neonates. There is a lack of research exploring nursing interns' experience in the NICU.
Purpose: This study aimed to explore the nursing interns' experience regarding their clinical placement in the NICU in Saudi Arabia.
Everyday life and boredom of people living with dementia in residential long-term care: a merged methods study.
BMC Geriatr
December 2024
Department of Health and Sport Sciences, Technical University of Munich, Georg-Brauchle-Ring 62, 80992, Munich, Germany.
Background: Everyday life in residential long-term care is widely portrayed as boring. However, empirical evidence on this topic remains limited, particularly for the vulnerable group of people living with dementia. A better understanding of everyday life and the associated experiences of boredom could facilitate the development of practical strategies to reduce boredom in this target group.
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