Tubulo-interstitial nephritis and uveitis syndrome in a 6-year-old boy: case report.

Ann Trop Paediatr

Department of Pediatrics, King Abdullah University Hospital, Jordan University of Science and Technology, Irbid, Jordan.

Published: June 2006

A 6-year-old boy presented with a 4-month history of anorexia, weight loss and fatigue and was found to have tubulo-interstitial nephritis and uveitis (TINU) syndrome. After 2 months of corticosteroid therapy, resolution of the uveitis was almost complete but renal function showed only partial improvement. He was still in renal failure 6 months after diagnosis, but there was no relapse of the uveitis. Although the prognosis of TINU in children and adults is reported to be excellent, the outcome in young children can be less favourable, probably owing to delayed diagnosis and initiation of treatment.

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http://dx.doi.org/10.1179/146532806X107502DOI Listing

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