Purpose: Economic assessment of an additional psychological intervention in the rehabilitation of patients with chronic low-back pain and evaluation of results by decision makers.
Methods: Piggy-back cost-utility analysis of a randomised clinical trial, including a bootstrap analysis. Costs were measured by using the cost accounting systems of the rehabilitation clinics and by surveying patients. Health-related quality of life was measured using the EQ-5D. Implications of different representations of the decision problem and corresponding decision rules concerning the cost-effectiveness plane are discussed.
Results: As compared with the 126 patients of the control arm, the 98 patients in the intervention arm gained 3.5 days in perfect health on average as well as 1219 euro cost saving. However, because of the uncertainty involved, the results of a bootstrap analysis cover all quadrants of the cost-effectiveness plane. Using maximum willingness-to-pay per effect unit gained, decision rules can be defined for parts of the cost-effectiveness plane. These have to be aggregated in a further valuation step.
Conclusions: Study results show that decisions on stochastic economic evaluation results may require an additional valuation step aggregating the various parts of the cost-effectiveness plane.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1055/s-2006-926717 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Cost-effectiveness of plasmapheresis and hemoperfusion in COVID-19 survivors: A six-month follow-up analysis after hospital discharge.
Ther Apher Dial
January 2025
Department of Health Care Management, Faculty of Health, Tehran Medical Science Branch, Islamic Azad University, Tehran, Iran.
Introduction: To evaluate the short- and long-term clinical and financial outcomes of apheresis in COVID-19 survivors after hospital discharge.
Methods: Intensive care unit-discharged patients were followed for 6 months. Vital signs, laboratory markers, quality of life, and direct medical costs were analyzed to calculate incremental cost-effectiveness ratios (ICER) and to plot cost-effectiveness planes and acceptability curves.
Neural network-based dynamic target enclosing control for uncertain nonlinear multi-agent systems over signed networks.
Neural Netw
December 2024
School of Aeronautics and Astronautics, University of Electronic Science and Technology of China, Chengdu, 611731, Sichuan, China; Aircraft Swarm Intelligent Sensing and Cooperative Control Key Laboratory of Sichuan Province, Chengdu, 611731, Sichuan, China. Electronic address:
Neural networks have significant advantages in the estimation of uncertainty dynamics, which can afford highly accurate prediction outcomes and enhance control robustness. With this in mind, this study presents a neural network-based method to investigate the uncertain target enclosing control problem for multi-agent systems over signed networks. Firstly, a nominal target enclosing controller is constructed by adding the target information component into the classical bipartite consensus error, in which the multi-agent system can be grouped to enclose the target from opposite sides.
View Article and Find Full Text PDFCost-Effectiveness of rTMS as a Next Step in Antidepressant Non-Responders: A Randomized Comparison With Current Antidepressant Treatment Approaches.
Acta Psychiatr Scand
December 2024
Center for Economic Evaluation, Trimbos Institute - Netherlands Institute of Mental Health and Addiction, Utrecht, The Netherlands.
Background: Although repetitive transcranial magnetic stimulation (rTMS) is an effective and commonly used treatment option for treatment-resistant depression, its cost-effectiveness remains much less studied. In particular, the comparative cost-effectiveness of rTMS and other treatment options, such as antidepressant medication, has not been investigated.
Methods: An economic evaluation with 12 months follow-up was conducted in the Dutch care setting as part of a pragmatic multicenter randomized controlled trial, in which patients with treatment-resistant depression were randomized to treatment with rTMS or treatment with the next pharmacological step according to the treatment algorithm.
Intercostal Nerve Cryoablation as an Effective Pain Management Strategy in the Nuss Procedure: Reducing Opioid Use and Hospital Stay.
Eur J Pediatr Surg
December 2024
Department of Anesthesiology, Nemours Children's Hospital, Orlando, Florida, United States.
Introduction: Erector spinae plane (ESP) blocks, thoracic epidural, and patient-controlled analgesia (PCA) have all been used for perioperative pain management in the Nuss procedure without a consensus on what modality produces the best outcomes. Intercostal nerve cryoablation (INC) is a relatively new modality that involves freezing the nerves to prevent pain during recovery. Our hypothesis is that using INC for the Nuss procedure will decrease opioid use, pain scores, and length of stay (LOS) but will increase cost compared with ESP block, thoracic epidural, and PCA.
View Article and Find Full Text PDFA Novel Training Model to Improve Diagnostic Accuracy of Cervical Fine-Needle Aspiration.
Head Neck
December 2024
Department of Otorhinolaryngology-Head and Neck Surgery, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland.
Introduction: This study aims to improve the diagnostic yield of cervical fine-needle aspiration (FNA) through training on a novel liver model. Ultrasonography-guided fine-needle aspiration (US-FNA) is crucial for diagnosing head and neck lumps but requires meticulous execution. Limited resources often hinder systematic teaching, making practical models essential for training.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!