In order to verify if the method for the titration of salivary secretory IgA (s-IgA) by the technical of radial immunodiffusion is trustworthy, have been carried out the precision tests in the series and among the series in two saliva samples with very different s-IgA concentrations, and precision and accuracy tests in the series and among the series using a solution with a known titre of IgA. The results of the first battery tests have shown a precision ranging from 93.04 to 95.43%. The results of the tests of the second battery have shown a precision ranging about 96% and an accuracy about 97%. The tested method is, therefore, sufficiently trustworthy.
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Talanta
January 2025
Pharmaceutical Chemistry Research Laboratory I, Department of Pharmaceutical Engineering & Technology, Indian Institute of Technology (Banaras Hindu University), Varanasi, 221005, India. Electronic address:
The cholinergic deficits and amyloid beta (Aβ) aggregation are the mainstream simultaneously observed pathologies during the progression of Alzheimer's disease (AD). Deposited Aβ plaques are considered to be the primary pathological hallmarks of AD and are contemplated as promising diagnostic biomarker. Herein, a series of novel theranostic agents were designed, synthesised and evaluated against cholinesterase (ChEs) enzymes and detection of Aβ species, which are major targets for development of therapeutics for AD.
View Article and Find Full Text PDFPhysiol Behav
January 2025
Department of Pedagogy, Psychology, Philosophy, University of Cagliari, Via Is Mirrionis 1, 09123 Cagliari, Italy.
This study was mainly aimed at exploring the effect of gender on the patterns of Physical Activty (PA) in older people living in an area of exceptional longevity, the so-called Sardinian Blue Zone. Furthermore, the study intended to investigate the nature of the relationships among PA metrics, cognitive measures, and age. One hundred and nine community-dwelling participants (M = 81.
View Article and Find Full Text PDFJ Hazard Mater
January 2025
State Key Laboratory of Urban Water Resource and Environment, Shenzhen Key Laboratory of Organic Pollution Prevention and Control, School of Civil and Environmental Engineering, Harbin Institute of Technology Shenzhen, Shenzhen 518055, PR China. Electronic address:
A series of core-shell In/H-Beta@Ce catalysts were synthesized by encapsulating In/H-Beta within an amorphous CeO shell and then evaluated for the selective catalytic reduction of NO by CH (CH-SCR) under challenging conditions with SO and HO. IB@Ce-2 achieved 57.7 % NO conversion at 625°C, representing a 23.
View Article and Find Full Text PDFJ Forensic Sci
January 2025
LIMA, Instituto de Química, Universidade de Brasília-UnB, Brasília, Brazil.
Fingermarks are important forensic evidence for identifying people. In this work, luminescent MOF [Eu(BDC)(HO)] (herein referred as EuBDC) was tested as a potential latent fingermark (LF) luminescent developer powder and its acute toxicity evaluated following OECD protocol 423. The results showed that the powder can develop groomed LF on materials such as leather, plastic, metal, glass, cardboard, and aluminum.
View Article and Find Full Text PDFFront Parasitol
May 2024
Department of Parasitology, Leiden University Medical Center, Leiden, Netherlands.
Detection of spp. DNA in gynaecological samples by quantitative real-time polymerase chain reaction (qPCR) is considered to be the reference diagnostic test for female genital schistosomiasis (FGS). However, qPCR needs expensive laboratory procedures and highly trained technicians.
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