Purpose: To evaluate optical coherence tomography as an objective diagnostic and follow-up method for central serous chorioretinopathy.
Methods: Observational descriptive study of 16 (sixteen) eyes of 16 patients with unilateral acute central serous chorioretinopathy. These patients had their visual acuity measured and complete ophthalmological examination was performed, including macular slit lamp examination, angiofluoresceinography and optical coherence tomography. No treatment was given to any patient.
Results: Of the 16 central serous chorioretinopathy eyes, 12 patients completed follow-up until total resolution of their disease. Age varied between 27 and 50 years, with mean age of 38.9 years. Most patients were male. On optical coherence tomography, neurosensorial retinal detachment was observed in all cases and 33.3% had retinal pigmented epithelium detachment. There was a significant difference regarding all studied variables. Visual acuity was better, macular thickness and volume diminished when the disease resolved.
Conclusion: Optical coherence tomography showed good efficacy to detect and measure macular changes in eyes with central serous chorioretinopathy, being useful in clinical evaluation during the disease's acute period and resolution.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1590/s0004-27492006000200006 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Identification of leakage sites in central serous chorioretinopathy using optical coherence tomography and the assessment of the characteristics of the biomarkers.
Retina
January 2025
Department of Ophthalmology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan.
Purpose: To identify optical coherence tomography (OCT)-based imaging biomarkers that can localize focal leakage points without fluorescein angiography in central serous chorioretinopathy (CSC).
Methods: This retrospective case-control study analyzed 119 consecutive patients (123 eyes) with CSC between April 2018 and February 2024, comprising 66 eyes with focal-leakage type and 57 eyes with diffuse-leakage type. We assessed leakage sites using OCT, and the proportions of OCT findings were compared between focal- and diffuse-leakage types.
Randomized phase II study of bevacizumab with weekly anetumab ravtansine or weekly paclitaxel in platinum-resistant/refractory high grade ovarian cancer (NCI trial).
Clin Cancer Res
January 2025
Princess Margaret Cancer Centre, Toronto, Ontario, Canada.
Purpose: Mesothelin (MSLN) is highly expressed in high grade serous/ endometrioid ovarian cancers (HGOC). Anetumab ravtansine (AR) is an antibody drug conjugate directed at MSLN antigen with a tubulin polymerization inhibitor. We assessed safety, activity and pharmacokinetics of the combination AR/bevacizumab (Bev) (ARB) versus weekly paclitaxel (wP)/Bev (PB) in patients with platinum resistant/refractory HGOC (prrHGOC).
View Article and Find Full Text PDFPrognostic significance of D-dimer, neuron-specific enolase, and lactate dehydrogenase changes in patients with severe traumatic brain injury: a logistic regression analysis.
J Pak Med Assoc
January 2025
Department of Neurosurgery, Baoding No.1 Central Hospital, Baoding, China.
The retrospective study was conducted at Baoding No.1 Central Hospital, China, and comprised data from July 2021 to January 2023, and aimed at exploring the relationship of neuron-specific enolase, D-dimer and lactate dehydrogenase with prognosis in patients with serous traumatic brain injury. Data of 100 patients was categorised into favourable prognosis group A having 50(50%) patients and unfavourable prognosis group B having 50(50%) patients, and was compared with as many healthy controls in group C.
View Article and Find Full Text PDF[Stress and other risk factors in central serous chorioretinopathy-A myth?].
Ophthalmologie
January 2025
Department of Ophthalmology, St. Franziskus Hospital, Muenster, Deutschland.
Since the initial description of central serous chorioretinopathy (CSC) by von Graefe in 1866, various risk factors for this condition have been described and discussed. In addition to established factors, such as the use of corticosteroids, psychosomatic factors, particularly stress, have increasingly come into focus in the literature. Studies have shown that psychological stress and emotional stressors not only impair well-being but also trigger physiological responses that could increase the risk of CSC.
View Article and Find Full Text PDFA 19-year-old asymptomatic woman.
Retin Cases Brief Rep
January 2025
New England Eye Center, Tufts Medical Center, Boston, MA.
Purpose: To describe a case of stellate multiform amelanotic choroidopathy (SMACH) with focal hyperfluorescence on indocyanine green angiography (ICGA).
Methods: Case report.
Results: A 19-year-old Caucasian woman was seen for an asymptomatic choroidal lesion.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!