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Assessing the threat of harboring a multi-resistant IncC plasmid and the efficacy of an antibiotic targeting LpxC.
Antimicrob Agents Chemother
January 2025
Univ. of Lille, CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, U1019-UMR 9017-CIIL-Center for Infection and Immunity of Lille, Lille, France.
Self-transmissible IncC plasmids rapidly spread multidrug resistance in many medically important pathogens worldwide. A large plasmid of this type (pIP1202, ~80 Kb) has been isolated in a clinical isolate of , the agent of plague. Here, we report that pIP1202 was highly stable in infected mice and fleas and did not reduce virulence in these animals.
View Article and Find Full Text PDFGoing 'meta': a systematic review of metacognition and functional neurological disorder.
Brain Commun
January 2025
Neurosciences and Cell Biology Research Institute, St George's University of London, London SW17 0RE, UK.
In functional neurological disorder (FND), there is a fundamental disconnect between an apparently intact nervous system and the individuals' ability to consistently perform motor actions, perceive sensory signals and/or access effective cognition. Metacognition, the capacity to self-evaluate cognitive performance, appears highly relevant to FND pathophysiology. Poor metacognition is a potential mechanism via which abnormal models of self and the state of the world could arise and persist unchecked.
View Article and Find Full Text PDFProtective effect of resveratrol on retinal damage in glaucoma: a systematic review and meta-analysis of preclinical studies.
Front Pharmacol
January 2025
Southwest Hospital/Southwest Eye Hospital, Third Military Medical University (Army Medical University), Chongqing, China.
Introduction: Resveratrol, a polyphenolic compound commonly found in natural plants and fruits, exhibits potential in preventing optic nerve damage in glaucoma, as indicated by several animal studies. However, there is presently a dearth of relevant evidence available for comprehensive summarization.
Methods: In this study, we conducted an extensive search across 7 electronic databases, encompassing all pertinent animal studies for a systematic review and meta-analysis.
Interactional practices accomplished by index-finger pointing directed at the addressee in Hebrew face-to-face interaction.
Front Psychol
January 2025
Department of Hebrew Language, Levinsky-Wingate Academic College, Tel Aviv, Israel.
This study uses Hebrew data to examine the practices accomplished by index-finger pointing toward the addressee, with a focus on interactional purposes beyond merely indexing the reference. The data were taken from the , which consists of video recordings of naturally occurring casual conversations collected between 2016 and 2023. By employing the methodologies of interactional linguistics and multimodal conversation analysis, the study elaborates on the social actions that are accomplished via this gesture, showing that pointing at the addressee in Hebrew talk-in-interaction can be explained from different perspectives.
View Article and Find Full Text PDFAre explorers greener? Investigating the role of personality traits, connectedness to nature and attitudes toward exploring in various pro-environmental behaviors.
Front Psychol
January 2025
Department of General Psychology, University of Padua, Padua, Italy.
Previous research has suggested that individual characteristics, such as personality traits, are crucial for pro-environmental behaviors. However, the joint role of more specific environment-related individual dispositions on various pro-environmental behaviors has not yet been investigated and is the aim of this study. A total of 649 adults (18-59 years old) assessed their pro-environmental behaviors, personality traits, the connectedness to nature, attitudes toward exploration, and spatial anxiety.
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