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| http://dx.doi.org/10.1172/JCI101414 | DOI Listing |
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In chronic experiments on dogs it was shown that verografin and iodamide are excreted from the body not only by filtration but by tubular excretion as well. The maximal transport of verografin and iodamide is significantly lower than that of cardiotrast. In experiments on rats similar results were obtained.
View Article and Find Full Text PDFThe effect of 5-hydroxymethyluracyl and dimephosphon on the tubular secretion of cardiotrast was studied on rats. The both drugs were shown to increase the tubular transport of xenobiotics.
View Article and Find Full Text PDF[Effect of dopamine on transport of organic substances in dog kidneys].
Fiziol Zh SSSR Im I M Sechenova
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I. v. infusion of dopamine increased diuresis, glomerular filtration rate, maximal reabsorption of glucose and tubular secretion of cardiotrast.
View Article and Find Full Text PDFKinetic modeling of the renal excretion of iodopyracet in the dog.
J Pharmacokinet Biopharm
February 1982
In a fundamental study on the kinetics of the urinary excretion of a number of agents secreted by the renal tubules of the mammalian kidney, we measured plasma levels of iodopyracet after intravenous application to male beagle dogs. The animals were anesthetized throughout the experiments with sodium pentobarbital, and provisions were made for the collection of blood and urine samples. In order to obtain a sufficiently high urine flow throughout the experiments, the dogs received a constant infusion of a solution containing 5% mannitol and 0.
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