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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC434576PMC
http://dx.doi.org/10.1172/JCI100034DOI Listing

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Introduction: COPD is characterised by airflow obstruction, expiratory airway collapse and closure causing expiratory flow limitation (EFL) and hyperinflation. Supine posture may worsen ventilatory function in COPD, which may cause hyperinflation to persist and contribute to symptoms of orthopnoea and sleep disturbance. Our aim was to determine the impact of supine posture on hyperinflation, dynamic elastance and EFL in COPD and healthy subjects.

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A Case of Post-malarial Postural Orthostatic Tachycardia Syndrome in a Young Woman of South Asian Origin.

Cureus

October 2024

Internal Medicine, School of Public Health and Health Professions, University at Buffalo, Buffalo, USA.

Postural orthostatic tachycardia syndrome (POTS) often manifests following an acute infection. This case study reports a post-malarial onset of POTS in a young female medical student who presented with tachycardia, dizziness, presyncope, several episodes of syncope, and dysautonomic symptoms. The diagnosis of POTS was established only four years later by a tilt table test.

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Introduction: Fibrotic interstitial lung diseases (ILD) are a heterogeneous group of conditions. Progression criteria include clinical, imaging, and/or lung functional decline. Currently, the 6-min walk test (6MWT) is considered the gold standard for assessing exercise-induced desaturation.

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Article Synopsis
  • Platypnea-orthodeoxia syndrome (POS) is a rare condition where a person experiences breathlessness and low oxygen levels when standing, but feels better when sitting or lying down, contrasting with orthopnea which worsens when lying flat.
  • A case study highlighted a 79-year-old woman with various health issues, including chronic kidney disease and a history of pulmonary embolism, who was found to have a severe patent foramen ovale (PFO) that likely contributed to her POS symptoms.
  • After successfully closing the PFO with a medical device, the patient showed significant improvement and was discharged within two days, emphasizing the importance of recognizing and treating POS to prevent serious health risks.
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Article Synopsis
  • * An 8-month-old boy experienced respiratory failure after liver transplant, and prone position ventilation improved his oxygenation following extubation challenges.
  • * The use of prone position in this case resulted in successful extubation and suggests that it could be a beneficial strategy for infants post-transplant, warranting further exploration of its application.
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