The protective effect of Feroniella lucida against lipid peroxidation was investigated. Bioassay-guided separation using rat brain as a model led to the isolation of a new antioxidant furanocoumarin named feroniellamin (6) along with five known coumarins. The structure of 6 was characterized by interpretation of spectroscopic data. Feroniellamin inhibited lipid peroxidation with an IC(50) value of 52 microM.
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| http://dx.doi.org/10.1002/ptr.1930 | DOI Listing |
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