An analysis of epidemiology of the post-traumatic infections of the locomotive system, prophylaxis and treatment in presented. Infections are the most severe complications of the open bone fractures and orthopedic surgery. An incident of inflammatory complications following the open bone fractures is very high (20% according to Burrie). An incidence of complications following orthopedic surgeries is somewhat lower--0.2-9.0%. Within 1976-1986, as much as 585 patients with chronic osteitis, including 222 patients with post-traumatic infections, were treated at the Department of Orthopedic Surgery, Medical Academy in Warsaw. Therapy depended on the general and local health status, and the types of surgery were diversified. The treatment included, first of all, radical removal of crushed and necrotic tissues, stabilization of the fractured bone fragments with the external stabilizer, AO plate or the Polish original method of the stable internal osteosynthesis--ZESPOL, decompression of the crack with the aid of permanent flow or suction drainage, systemic or local antibiotic therapy, administration of vasodilating agents, and the primary skin plasty in some cases.
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BMC Microbiol
January 2025
Engineering Research Center of Health Emergency, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing, 210009, China.
Background: Wastewater systems are usually considered antibiotic resistance hubs connecting human society and the natural environment. Antibiotic usage can increase the abundance of both ARGs (antibiotic resistance genes) and MGEs (mobile gene elements). Understanding the transcriptomic profiles of ARGs and MGEs remains a major research goal.
View Article and Find Full Text PDFLife Sci Space Res (Amst)
February 2025
Institute of Biomedical Problems of the Russian Academy of Sciences, 76A Khoroshevskoye shosse, 123007, Moscow, Russian Federation.
One of the most problematic goals for radiation safety during spaceflight is an assessment of additional doses received by astronauts during extravehicular activity (EVA). The Pille-ISS thermoluminescent dosimeter developed by the predecessor of the Hungarian Research Network (HUN-REN) Centre for Energy Research (Budapest, Hungary) is designed for the routine dose measurements not only inside the spacecraft compartments, but also for personal dosimetric control for EVA. During almost two decades of the International Space Station (ISS) operation, the unique set of 131 EVA doses were recorded in different conditions, such as: solar activity, ISS trajectory along the South Atlantic Anomaly (SAA), and shielding conditions provided by two kinds of spacesuits: the Extravehicular Mobility Unit (EMU) and Orlan.
View Article and Find Full Text PDFLife Sci Space Res (Amst)
February 2025
Department of General Surgery, the 306th Hospital of PLA-Peking University Teaching Hospital, Beijing 100101, PR China; Department of General Surgery, the Ninth Medical Center of PLA General Hospital, Beijing 100101, PR China. Electronic address:
Background: Currently, there is limited research on the impact of abdominal infection on intestinal damage under microgravity conditions. Cordyceps polysaccharide (CPS), the main active ingredient of Cordyceps, has demonstrated various pharmacological effects, including anti-inflammatory, antioxidant, and immunomodulatory properties. Moxifloxacin (MXF) is a fourth-generation quinolone antibiotic that is believed to have a dual regulatory effect on immune system activation and suppression.
View Article and Find Full Text PDFJMIR Form Res
January 2025
Section for Physiotherapy, Division of Medicine, Oslo University Hospital, Oslo, Norway.
Background: The use of mobile health interventions, such as apps, are proposed to meet the challenges faced by preventive health care services due to the increasing prevalence of type 2 diabetes (T2D). Thus, we developed and conducted initial feasibility testing of the Plunde app for promoting and monitoring individual goals related to lifestyle change for people at risk of T2D.
Objective: The primary aim of this study was to assess the feasibility of an app for promoting lifestyle change in people at risk of T2D.
J Hosp Infect
January 2025
Institute of Patient care, Radboud University Medical Center, Nijmegen, The Netherlands.
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