Interatrial block (IAB) (P wave > or =110 milliseconds) is a potent correlate of atrial tachyarrhythmias, left atrial electromechanical dysfunction, and embolism. IAB has been demonstrated to be highly prevalent in the general hospital population, but no investigation has addressed this in the elderly community outside the hospital. We appraised the prevalence of IAB in a service of the Program of All-Inclusive Care for the Elderly (PACE), the Elder Service Plan (ESP). Of the 202 ESP members in Worcester, MA, 167 (ages 61-103 years; female 81.4%) who had current 12-lead electrocardiograms were evaluated for IAB, and an age-based comparison was made between those with and without IAB. Of those patients with current electrocardiograms, 148 (88.6%) showed sinus rhythm and 72 (48.6%) depicted IAB: 20% in patients aged 60-69 years, 39.5% aged 70-79 years, 56.8% aged 80-89 years, and 50% in those 90 years and older. Given its sequelae of anatomic and pathophysiologic consequences, prompt recognition of IAB in a high-risk group such as that in the PACE community (48.6% prevalence) is important, especially for anticipation of atrial fibrillation and possible embolism.
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http://dx.doi.org/10.1111/j.1076-7460.2006.04518.x | DOI Listing |
Heart Rhythm
January 2025
Department of Molecular Biosciences, University of California, Davis, CA, USA; Department of Basic Sciences, California Northstate University, Elk Grove, CA. Electronic address:
Background: Friedreich's ataxia (FA) is a rare inherited neuromuscular disorder, where most patients die from lethal cardiomyopathy and arrhythmias. Mechanisms leading to arrhythmic events in FA patients are poorly understood.
Objective: This study aims to examine cardiac electrical signal propagation in mouse model of FA with severe cardiomyopathy and evaluate effects of omaveloxolone (OMAV), the first FDA-approved therapy.
JTCVS Open
December 2024
Department of Cardiac Surgery, Klinikum Nürnberg, Paracelsus Medical University, Nuremberg, Germany.
Objectives: This study aims to investigate the association between interatrial conduction block and postoperative atrial fibrillation, which can precipitate acute cardiopulmonary instability and is associated with subsequent heart failure, stroke, and mortality following cardiac surgery.
Methods: Perioperative 12-channel electrocardiograms from 3405 patients undergoing myocardial revascularization, valve surgery, aortic surgery, or combinations thereof, were considered. Clinical and electrographic parameters were compared between patients with and without atrial fibrillation, and significant variables were analyzed using univariate and multivariate logistic regression.
Pacing Clin Electrophysiol
December 2024
Cardiology Department, Hospital General Universitario Gregorio Marañón, Instituto de Investigación Sanitaria Gregorio Marañón, CIBERCV, Madrid, Spain.
Ann Noninvasive Electrocardiol
January 2025
Heart Centre & Department of Cardiovascular Diseases and Institute of Medical Sciences, General Hospital of Ningxia Medical University, Yinchuan, People's Republic of China.
Background: After acute myocardial infarction (AMI), it is common to observe new-onset atrial fibrillation (NOAF), which is often related to a negative prognosis. Some P-wave variables (P-wave duration [PWD], P-wave amplitude, and interatrial block [IAB]), reflecting the process of electrical and structural remodeling, could predict the risk of atrial fibrillation (AF). This study aimed to assess the predictive value of P-wave variables for post-AMI NOAF.
View Article and Find Full Text PDFInterdiscip Cardiovasc Thorac Surg
December 2024
Paracelsus Medical University, Nuremberg, Germany.
Objectives: Atrial fibrillation is common complication after heart surgery potentially leading to chronic atrial fibrillation, heart failure, and mortality. The aim of this study was to explore the relationship between preoperative interatrial block and the occurrence of postoperative atrial fibrillation.
Methods: Perioperative 12-channel ECGs of patients in sinus rhythm, scheduled for heart surgery including bypass and/or valve surgery were analysed.
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