[The evaluation of the late effect of the multiple administration of immunoglobulin on hepatitis A morbidity in organized collectives].

The analysis of influence in multiple injections of immunoglobulin (IG) on a level of morbidity and the efficiency of IG prophylaxis against hepatitis A in organized collectives made it possible to reveal the following common features: there is a direct dependency between morbidity level and average geometrical anti-IG titers, as well as the number of injections; there is inverse dependency between IG protection activity and the same factors; there is a lack of prophylaxis effect in anti-IG titers 1:32 or more. The authors frame a hypothesis that the reason of epidemic upgrowth of long standing hepatitis A morbidity dynamics in military collectives was conditioned by the wide application of IG in the 70s for children and teenagers.