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| http://dx.doi.org/10.1186/cc4906 | DOI Listing |
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Early extracorporeal membranous oxygenation and burn excision in severe burn and inhalation injury.
Scars Burn Heal
December 2024
Department of Surgery, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Article Synopsis
- ECMO (extracorporeal membranous oxygenation) is explored as a treatment option for patients with severe ARDS, particularly in burn cases where previous experience is limited.
- A case study details a 40-year-old woman with significant burns and severe inhalation injury who was placed on veno-venous ECMO for over 21 days while undergoing multiple surgical procedures and receiving extensive blood product transfusions.
- The report emphasizes the challenges and complexities of managing ECMO support during burn excision surgery, highlighting the need for further research on patient management strategies and the timing of interventions in such cases.
Awake veno-venous extracorporeal membrane oxygenation: practical aspects and considerations.
Minerva Anestesiol
December 2024
Department of Medical Science, Surgery and Neurosciences, Anesthesia and Intensive Care Unit, University Hospital of Siena, Siena, Italy.
Veno-venous extracorporeal membrane oxygenation (ECMO) is a life-saving technique in the armamentarium of critical care medicine. It involves extracorporeal blood circulation outside the body, providing temporary respiratory support while allowing the lungs to heal. Traditionally, patients undergoing ECMO require sedation to minimize discomfort and facilitate mechanical ventilation.
View Article and Find Full Text PDFImmediate postinjury extracorporeal carbon dioxide removal reduces ventilator requirements and mitigates acute respiratory distress syndrome in swine.
J Trauma Acute Care Surg
December 2024
From the Autonomous Reanimation and Evacuation Research Program (A.I.B., T.R.R., B.M.B., D.S.W.), The Geneva Foundation, San Antonio; US Army Institute of Surgical Research (B.S.J., C.N., L.C.C.), Joint Base San Antonio-Fort Sam Houston, Texas; Division of Traumatology, Surgical Critical Care and Emergency Surgery (J.W.C.), Penn Presbyterian Medical Center, Philadelphia, Pennsylvania; Seastar Medical (K.K.C.), Denver, Colorado; and Division of Trauma and Emergency Surgery (L.C.C.), University of Texas San Antonio, San Antonio, Texas.
Background: Awareness of ventilator-induced lung injury contributed to increased use of extracorporeal interventions, but not immediately after injury, before acute respiratory distress syndrome (ARDS) ensues. Our objective was to evaluate the role of venovenous extracorporeal carbon dioxide removal (ECCO2R) in management of mechanically ventilated swine with smoke inhalation injury and 40% body surface area burns.
Methods: Yorkshire swine (n = 29, 43.
Prevention of Air Embolism in Extracorporeal Membrane Oxygenation Systems: An In Vitro Study on Protection of Central Venous Catheter Lumen.
Medicina (Kaunas)
November 2024
Center for Intensive Internal Medicine, University Medical Center, Zaloska 7, 1000 Ljubljana, Slovenia.
Article Synopsis
- * It found that using interventions like a closed three-way stopcock or clave significantly prevented air entry, while small volumes of air (1 mL) could still cause dysfunction at certain pump speeds.
- * Auditory cues, such as a hissing sound, were identified as important early warnings for detecting air presence in the circuit, contributing to the overall safety of ECMO systems and reducing the risk of air embolism.
Angiopoietin II in Critically Ill Septic Patients: A Post Hoc Analysis of the DRAK Study.
Biomedicines
October 2024
Department of Anaesthesiology, University Hospital, LMU Munich, Marchioninistrasse 15, 81377 Munich, Germany.
Article Synopsis
- Angiotensin II (Ang-II) is crucial in causing microcirculatory dysfunction, especially in patients with sepsis and acute kidney injury, leading to uncertainty about factors affecting its concentration in the early sepsis phase.
- A study measured Ang-II levels in 171 sepsis patients post-antibiotic treatment using various statistical methods to identify correlations with clinical factors.
- Results showed a high median Ang-II concentration, with significant correlations found including kidney replacement therapy and fluid balance, indicating sick patients with kidney treatment had notably higher Ang-II levels compared to those on ECMO.
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