Key clinical trials in gynaecological oncology.

Eur J Surg Oncol

Nuffield Department of Obstetrics and Gynaecology, John Radcliffe Hospital, Headington, Oxford OX3 9DU, UK.

Published: October 2006

Aims: To review the most important clinical trials which have impacted the management of gynaecological cancers, in conjunction with some ongoing studies of interest.

Methods: PubMed and Cochrane databases were searched to find clinical trials and meta-analyses in vulva, cervical, endometrial and ovarian cancers. Other pertinent literature was also used.

Results: The majority of trials related to ovarian and cervical cancers, and the least associated with vulval cancer.

Conclusions: To ensure evidence based medicine, trials in gynaecological cancers must be supported. Notably, surgical trials are on the increase in the last decade, but are still a minority when compared with non-surgical interventions.

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http://dx.doi.org/10.1016/j.ejso.2006.03.038DOI Listing

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