Post kala-azar dermal leishmaniasis (PKDL) occurs occasionally after successful cure of visceral leishmaniasis. Twelve patients with diagnosis consistent with PKDL were seen at Clinical Research Centre from 1981 to 1985. Clinical presentation ranged from macular hypopigmented lesion to generalized nodular lesions. All lesions cleared either by self-cure or by treatment with sodium stibogluconate.
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Article Synopsis
- Post Kala-azar Dermal Leishmaniasis (PKDL) emerges as a complication of visceral leishmaniasis (VL), posing challenges for disease management and ongoing elimination efforts due to its potential for ongoing transmission.
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- The findings suggest that activated neutrophils may significantly influence the inflammatory environment in PKDL, highlighting the need for further understanding of their role in the disease's progression and treatment.
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