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Background: Crystal methamphetamine abuse is a growing concern due to its significant adverse effects on various organ systems.

Case Description: This report presents a rare case of pneumomediastinum, pneumoretroperitoneum and subcutaneous emphysema resulting from crystal methamphetamine abuse. The exact mechanism linking methamphetamine abuse to pneumomediastinum remains ambiguous.

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Article Synopsis
  • Myocardial dissection is a rare but serious complication of ischaemic heart disease, characterized by a haematoma forming within the cardiac muscle, often triggered by factors such as increased wall tension and reduced tensile strength.
  • A case study highlights a 37-year-old male, who developed myocardial dissection following an ST elevation infarction after years of substance abuse, including heroin and methamphetamines, which might be linked to his condition.
  • The patient presented with symptoms of heart failure, and diagnostic tests revealed severe heart dysfunction and a mass in the heart, leading to treatment with diuretics and medical therapy instead of surgery due to high operative risk.
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Impacts of the COVID-19 pandemic on the availability and retail price of unregulated drugs in Vancouver, Canada: An interrupted time-series analysis, 2018-2022.

Int J Drug Policy

December 2024

British Columbia Centre on Substance Use, Vancouver, Canada; Faculty of Health Sciences, Simon Fraser University, Burnaby, BC, Canada; Department of Medicine, University of British Columbia, Vancouver, BC, Canada. Electronic address:

Background: Impacts of the COVID-19 pandemic on unregulated drug markets in North America have not been well characterized. We sought to estimate potential changes in the availability and retail price of unregulated drugs in Vancouver, Canada pre- vs. post-emergence of the COVID-19 pandemic.

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Methamphetamine-induced cardiotoxicity: in search of protective transcriptional mechanisms.

Herz

December 2024

Department of Psychosomatic Medicine and Psychotherapy, University of Göttingen, Waldweg 33, 37073, Göttingen, Germany.

Crystalline methamphetamine hydrochloride is an illegal drug with a high addictive potential, better known by its colloquial name "ice" or "crystal meth". The abuse of this drug has led to significant health problems worldwide. Like other amphetamine-type stimulants, chronic consumption of methamphetamine leads to direct toxic effects on the central nervous system, causing cognitive impairment, depressive behavior, and other severe neurological or psychiatric symptoms.

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2S/LGBTQ+ youth substance use and pathways to homelessness: A photovoice study.

Int J Drug Policy

November 2024

British Columbia Centre on Substance Use, Vancouver, Canada; École de Santé Publique, Université de Montréal, Montréal, Canada; Centre de Recherche en Santé Publique (CReSP), Montréal, Canada.

Background: Studies have posited that substance use is associated with, or contributes to, homelessness for 2S/LGBTQ+ youth. However, interconnections between these issues are poorly articulated.

Methods: This community-based photovoice study describes the narratives used by 2S/LGBTQ+ youth about how substance use featured in their pathways to homelessness.

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