We identified the cytolethal distending toxin V (CDT-V) gene cluster in 19 (4.9%) of 391 enterohemorrhagic Escherichia coli O157:H7. cdt-V+ strains belonged to five phage types (PTs) and were most frequent within PTs 14 and 34. CDT-V was expressed in all but two cdt-V+ strains and was lethal to cultured endothelial cells. Subtyping schemes should include cdt-V as a marker to differentiate E. coli O157:H7 even within the same phage type.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1479162 | PMC |
| http://dx.doi.org/10.1128/JCM.44.5.1844-1846.2006 | DOI Listing |
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