The effect of 10 mg nifedipine on cerebral oxygenation was studied in healthy individuals. The duration of investigation was 30 min or 3 h. Nifedipine appreciably increased cerebral oxygenation (by 5.9%, p<0.01) against the background of significant increase in heart rate and negligible decrease in systolic arterial pressure. Drowsiness was the most serious side effect of nifedipine (observed in 52.8% examined subjects).
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| http://dx.doi.org/10.1007/s10517-005-0509-6 | DOI Listing |
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