Inhibition of glycine oxidation by carboxymethoxylamine, methoxylamine, and acethydrazide.

Plant Physiol

Department of Bacteriology and Biochemistry, University of Idaho, Moscow, Idaho 83843.

Published: March 1985

Carboxymethoxylamine (amino-oxyacetate), methoxylamine, and acethydrazide are shown to be effective, although not completely specific, inhibitors of glycine oxidation by the isolated glycine decarboxylase multienzyme complex, mitochondria, protoplasts, and leaf discs from peas. The inhibition probably results from a reaction between these compounds and the pyridoxal 5-phosphate cofactor of the enzyme.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1064602PMC
http://dx.doi.org/10.1104/pp.77.3.786DOI Listing

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