In alert rabbits, pulse stimulation of the visual cortex interfered with the formation of short latency responses in superior colliculus. The effect of visual cortex upon the superior colliculus function may have a phasic inhibitory character. Blockade of the RF adrenergic apparatus enhances the inhibitory effect, whereas stimulation of the RF by anodal current induces an opposite effect. The character of cortical influence upon the superior colliculus function seems to depend on initial functional state of cerebral unspecific systems.
Download full-text PDF |
Source |
---|
Neuroimage
January 2025
Integrated Program in Neuroscience, McGill University, Montreal, Quebec, Canada; Department of Physiology, McGill University, Montreal, Quebec, Canada. Electronic address:
In response to sensory deprivation, the brain adapts to efficiently navigate a modified perceptual environment through a process referred to as compensatory crossmodal plasticity, allowing the remaining senses to repurpose deprived regions and networks. A mechanism that has been proposed to contribute to this plasticity involves adaptations within subcortical nuclei that trigger cascading effects throughout the brain. The current study uses 7T MRI to investigate the effect of perinatal deafness on the volumes of subcortical structures in felines, focusing on key sensory nuclei within the brainstem and thalamus.
View Article and Find Full Text PDFAntioxidants (Basel)
December 2024
Ramon Castroviejo Institute for Ophthalmic Research, Complutense University of Madrid, 28040 Madrid, Spain.
Glaucoma is a neurodegenerative disease characterized by the loss of retinal ganglion cells (RGCs), with intraocular pressure (IOP) being its primary risk factor. Despite controlling IOP, the neurodegenerative process often continues. Therefore, substances with neuroprotective, antioxidant, and anti-inflammatory properties could protect against RGC death.
View Article and Find Full Text PDFSci Rep
January 2025
Werner Reichardt Centre for Integrative Neuroscience, University of Tübingen, Otfried-Müller Str. 25, 72076, Tübingen, Germany.
Microsaccades are associated with enhanced visual perception and neural sensitivity right before their onset, and this has implications for interpreting experiments involving the covert allocation of peripheral spatial attention. However, the detailed properties of premicrosaccadic enhancement are not fully known. Here we investigated how such enhancement in the superior colliculus depends on luminance polarity.
View Article and Find Full Text PDFCurr Biol
January 2025
Department of Psychology, University of Virginia, Charlottesville, VA 22904, USA; Department of Biology, University of Virginia, Charlottesville, VA 22904, USA. Electronic address:
Visual motion is a crucial cue for the brain to track objects and take appropriate actions, enabling effective interactions with the environment. Here, we study how the superior colliculus (SC) integrates motion information using asymmetric plaids composed of drifting gratings of different directions and speeds. With both in vivo electrophysiology and two-photon calcium imaging, we find that mouse SC neurons integrate motion direction by performing vector summation of the component gratings.
View Article and Find Full Text PDFUnlabelled: Multiple sources innervate the visual thalamus to influence image-forming vision prior to the cortex, yet it remains unclear how non-retinal and retinal input coordinate to shape thalamic visual selectivity. Using dual-color two-photon calcium imaging in the thalamus of awake mice, we observed similar coarse-scale retinotopic organization between axons of superior colliculus neurons and retinal ganglion cells, both providing strong converging excitatory input to thalamic neurons. At a fine scale of ∼10 µm, collicular boutons often shared visual feature preferences with nearby retinal boutons.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!