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| http://dx.doi.org/10.1104/pp.45.2.233 | DOI Listing |
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Communicating with Stakeholders to Identify High-Impact Research Directions for Non-Targeted Analysis.
Anal Chem
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Center for Devices and Radiological Health, U.S. Food and Drug Administration, 10903 New Hampshire Avenue, Silver Spring, Maryland 20993, United States.
Non-targeted analysis (NTA) using high-resolution mass spectrometry without defined chemical targets has the potential to expand and improve chemical monitoring in many fields. Despite rapid advancements within the research community, NTA methods and data remain underutilized by many potential beneficiaries. To better understand barriers toward widespread adoption, the Best Practices for Non-Targeted Analysis (BP4NTA) working group conducted focus group meetings and follow-up surveys with scientists (n = 61) from various sectors (e.
View Article and Find Full Text PDFGenetic diversity, population structure in a historical panel of Brazilian soybean cultivars.
PLoS One
January 2025
The Sainsbury Laboratory-TSL, University of East Anglia, Norwich, United Kingdom.
Soybean [Glycine max (L.) Merrill] is one of the most widely grown legumes in the world, with Brazil being its largest producer and exporter. Breeding programs in Brazil have resulted from multiple cycles of selection and recombination starting from a small number of USA cultivar ancestors in the 1950s and 1960s years.
View Article and Find Full Text PDFExplanatory review on DDR inhibitors: their biological activity, synthetic route, and structure-activity relationship.
Mol Divers
January 2025
Integrated Drug Discovery Centre, Department of Pharmaceutical Chemistry, Acharya & BM Reddy College of Pharmacy, Bengaluru, 560107, Karnataka, India.
Discoidin domain receptors (DDR) are categorized under tyrosine kinase receptors (RTKs) and play a crucial role in various etiological conditions such as cancer, fibrosis, atherosclerosis, osteoarthritis, and inflammatory diseases. The structural domain rearrangement of DDR1 and DDR2 involved six domains of interest namely N-terminal DS, DS-like, intracellular juxtamembrane, transmembrane juxtamembrane, extracellular juxtamembrane intracellular kinase domain, and the tail portion contains small C-tail linkage. DDR has not been explored to a wide extent to be declared as a prime target for any particular pathological condition.
View Article and Find Full Text PDFAdvancing research and policy in climate and health in the Nordic countries: Key challenges and opportunities for future action.
Scand J Public Health
January 2025
Department for Air Quality and Noise, Divison for Climate and Environmental Health.
Aim: This editorial presents state of the art developments in research and policy in the newly emerging field of climate and health and examines the gaps in research, the relevance of Nordic research in a global context, and the need to place the climate-health agenda in the policy space.
Methods: We use a set of articles from the Special Issue on 'Climate change and health in the Nordic countries' in this journal to understand current research in climate and health. We identify three emerging areas that characterize the current focus of research: modelling climate change-induced exposures; health cross-linkages of the climate health agenda and targeted communication.
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