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People with HIV (PWH) are living longer and experiencing a greater burden of morbidity from non-AIDS-defining conditions. Chronically treated HIV disease is associated with ongoing systemic inflammation that contributes to the development of chronic conditions (eg, cardiovascular disease) and geriatric syndromes (eg, frailty). Apart from HIV disease, a progressive increase in systemic inflammation is a characteristic feature of biologic aging, a process described as "inflammaging.

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Background: Myelomeningocele and sagittal craniosynostosis are 2 neurosurgical pathologies with complications such as increased intracranial pressure (ICP) and hydrocephalus. While the 2 defects commonly occur independently, their simultaneous occurrence is exceptionally rare.

Observations: The authors report the case of a newborn male diagnosed with a simultaneous myelomeningocele and sagittal craniosynostosis.

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Sub-5 Ångstrom Porosity Tuning in Calixarene-Derived Porous Liquids via Supramolecular Complexation Construction.

Angew Chem Int Ed Engl

January 2025

Oak Ridge National Laboratory, Chemical Sciences Division, UNITED STATES OF AMERICA.

Precise sub-Ångstrom-level porosity engineering, which is appealing in gas separations, has been demonstrated in solid carbon, polymer, and framework materials but rarely achieved in the liquid phase. In this work, a gas molecular sieving effect in the liquid phase at sub-5 Ångstrom scale is created via sophisticated porosity tuning in calixarene-derived porous liquids (PLs). Type II PLs are constructed via supramolecular complexation between the sodium salts of calixarene derivatives and crown ether solvents.

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Article Synopsis
  • PAH can cause serious ocular conditions like CRVO and CilRAO due to high blood pressure in the lungs affecting blood flow to the eyes.
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  • Treatment with Bosentan and traditional Chinese medicine led to significant vision improvement, highlighting the importance of addressing cardiovascular issues to prevent eye complications and the need for a comprehensive approach in such complex cases.
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Reinforcing chemically treated human hair with citric acid.

Int J Cosmet Sci

January 2025

L'Oréal Research & Innovation, Aulnay-sous-Bois, France.

Article Synopsis
  • The study aimed to analyze how citric acid (CA) reinforces chemically treated hair by evaluating its effects on different treatment types like bleaching and perming.
  • Various physical and chemical testing methods showed that CA significantly enhances hair's structural integrity, increases its mechanical properties, and reduces harmful calcium levels in the hair.
  • Results suggest that the effectiveness of CA is influenced by the specific type of prior chemical treatment, with implications for improving hair care products that target damaged hair.
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