The first synthesis of [U-13C, 15N] labeled phosphotyrosine is described. Preliminary studies toward the binding of phosphotyrosine to an SH2 domain have been performed by means of heteronuclear NMR.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bmcl.2006.04.021DOI Listing

Publication Analysis

Top Keywords

facile synthesis
4
synthesis application
4
application uniformly
4
uniformly 13c
4
13c 15n-labeled
4
15n-labeled phosphotyrosine
4
phosphotyrosine ligand
4
ligand binding
4
binding studies
4
studies synthesis
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!