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Nevus of Hori in African patients: an entity that is most likely underdiagnosed in clinical practice.
Int J Womens Dermatol
March 2025
Private Practice, Pretoria, South Africa.
Background: Nevus of Hori (HN) has been primarily reported in patients of Eastern Asian descent, with a paucity of data regarding HN occurring in African patients. In this study, we report on South African patients with HN initially thought to have melasma.
Objective: To characterize the histopathological and clinical phenotypes of HN in African patients.
Oculodermal melanocytosis in Asian Indian patients: Prevalence, clinical presentation, and association with choroidal melanoma.
Indian J Ophthalmol
January 2025
The Operation Eyesight Universal Institute for Eye Cancer, L V Prasad Eye Institute, Hyderabad, Telangana, India.
Objective: To study the prevalence, clinical presentation, treatment, and follow-up of ocular (dermal) melanocytosis (ODM) and its association with choroidal melanoma (CM) in Asian Indian patients.
Methods: This was a retrospective case series of patients with ODM conducted in a quaternary eye care center.
Results: Of the total 1.
Phenotypic Spectrum of GNA11 R183C Mosaicism.
Pediatr Dermatol
December 2024
Pediatric Dermatology Department, Barcelona Children's Hospital Sant Joan de Déu, Barcelona, Spain.
Background: Many vascular anomalies harbor postzygotic somatic variants in GNAQ and GNA11; however, the phenotype of specific G-protein variants has not been well described. We report the clinical characteristics of 17 patients with a GNA11 R183C variant.
Methods: This case series is derived from a multinational cohort of vascular anomaly patients whose pathogenic mutations were identified using high-depth next generation sequencing.
Patchy Dermal Melanocytosis: Differential Diagnosis and Management.
J Cosmet Dermatol
November 2024
Department of Laser and Aesthetic Medicine, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Article Synopsis
- Nevus of Ito and Mongolian spots are forms of patchy dermal melanocytosis that can look similar, making diagnosis tricky for doctors.
- The review highlights differences in their epidemiology, clinical features, and treatment options, noting that Mongolian spots usually fade with age while nevus of Ito can persist and turn malignant.
- Innovative treatments, such as lower-energy lasers, are becoming more effective, especially for children, indicating a promising shift in managing these skin conditions.
Blue Nevus Associated With Acquired Dermal Melanocytosis on the Back.
Cureus
July 2024
Pathology, Kitami Red Cross Hospital, Kitami, JPN.
Article Synopsis
- Dermal melanocytosis refers to a variety of skin conditions involving specialized pigment-producing cells (melanocytes), presenting as either nodular lesions like blue nevi or flat patches.
- A case study of a 46-year-old Japanese woman revealed a black nodule indicative of a blue nevus amidst a blue-grey hyperpigmented area, with lab results confirming both conditions.
- The combination of blue nevus and acquired dermal melanocytosis is rare, suggesting that understanding these unique cases is essential for proper diagnosis and treatment.
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