Upper respiratory tract involvement of sarcoidosis in the Turkish population.

Otolaryngol Head Neck Surg

Department of Lung Diseases, Cerrahpaşa Medical Faculty, University of Istanbul, Istanbul, Turkey.

Published: May 2006

AI Article Synopsis

  • The study examined 12 out of 546 sarcoidosis patients (2.19%) with upper respiratory tract (URT) involvement over a 40-year period.
  • Among these cases, the most frequent URT issue was laryngeal involvement (5 patients), followed by sinonasal tract problems (4 patients) and other sites.
  • Overall, URT involvement is considered rare in systemic sarcoidosis, with laryngeal issues being the most common among the Turkish population.

Article Abstract

Principles And Methods: Upper respiratory tract (URT) involvement is rare in sarcoidosis. In this descriptive study, we retrospectively evaluated the clinical and demographic features of 12 (2.19%) patients with URT involvement out of the 546 sarcoidosis patients with follow-up visits at our center within the last 40-year period.

Results: Out of the 546 patients, 12 (2.19%) had upper respiratory tract involvement, 5 (0.91%) had laryngeal involvement, 4 (0.73%) had sinonasal tract involvement, 2 (0.36) patients had salivary gland involvement, and 1 patient had tonsillary involvement. The number of stage 0 subjects among other sarcoidosis patients was significantly lower than that among those with URT involvement.

Conclusions: URT involvement is rarely diagnosed in patients with systemic sarcoidosis. The most common site for URT involvement among the Turkish population is the larynx, followed by the sinonasal tract.

Ebm Rating: C-4.

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Source
http://dx.doi.org/10.1016/j.otohns.2006.01.011DOI Listing

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