In this paper, we show that replicator dynamics can be used as an exploratory analysis tool to detect subregions of cortical areas on the basis of the similarity between fMRI time series. As similarity measure, we propose to use canonical correlation, a multivariate extension to the typically employed Pearson's correlation coefficient. We applied the replicator process to data obtained from two different experimental paradigms in the search for subregions within the left lateral frontal cortex (LFC). In both cases, the replicator process resulted in a parcellation that corresponds to a recently suggested subdivision of the LFC in anterior-posterior direction. Most notably, these results were very consistent when compared across different measurements of a single subject and across a group of subjects.
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| http://dx.doi.org/10.1016/j.neuroimage.2006.02.039 | DOI Listing |
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