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Implementation of a Laboratory Information Management System (LIMS) for microbiology in Timor-Leste: challenges, mitigation strategies, and end-user experiences.
BMC Med Inform Decis Mak
January 2025
Global and Tropical Health Division, Menzies School of Health Research, Charles Darwin University, Dili, Timor-Leste.
Background: Effective diagnostic capacity is crucial for clinical decision-making, with up to 70% of decisions in high-resource settings based on laboratory test results. However, in low- and middle-income countries (LMIC) access to diagnostic services is often limited due to the absence of Laboratory Information Management Systems (LIMS). LIMS streamline laboratory operations by automating sample handling, analysis, and reporting, leading to improved quality and faster results.
View Article and Find Full Text PDFUsing a participatory approach to identify priorities to advance LHS implementation at an academic medical center.
Learn Health Syst
January 2025
Introduction: Like many other academic medical centers, the University of Alabama at Birmingham (UAB) aspires to adopt learning health system (LHS) principles and practices more fully. Applying LHS principles establishes a culture where clinical and operational practices constantly generate questions and leverage information technology (IT) and methodological expertise to facilitate systematic evaluation of care delivery, health outcomes, and the effects of improvement initiatives. Despite the potential benefits, differences in priorities, timelines, and expectations spanning an academic medical center's clinical care, administrative operations, and research arms create barriers to adopting and implementing an LHS.
View Article and Find Full Text PDFStroke Prevention in Hispanic Children with Sickle Cell Anemia: the SACRED trial.
Blood Adv
January 2025
Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States.
Sickle cell anemia (SCA) is recognized globally, but little is known about affected Hispanic populations. In partnership with Dominican Republic, a Hispanic Caribbean Island with a large SCA population, a TCD screening program provided hydroxyurea to children with conditional velocities. Building local capacity, ten Dominican medical graduates were certified in TCD examinations and trained in hydroxyurea management.
View Article and Find Full Text PDFProposals for the Implementation of a Multidimensional Platform That Allows the Advancement of Oncology Nursing in the Latin American Environment (The INCREASE Proposal).
JCO Glob Oncol
January 2025
Direction of Research and Education, Luis Carlos Sarmiento Angulo Cancer Treatment and Research Center-CTIC/El Bosque University, Bogotá, Colombia.
Purpose: Cancer constitutes a significant global health challenge, with projections indicating a continued increase in its prevalence in the foreseeable future. This trend is particularly pronounced in Latin America (LATAM), where the cancer burden has increased substantially over the coming decades. Concurrently, nursing, which represents the largest segment of the health care workforce globally, is important for addressing the multifaceted challenges posed by cancer care, particularly in low- and middle-income countries (LMICs).
View Article and Find Full Text PDFFindings from an expert focus group on psychotropic medication deprescribing practices for children and youth with complex needs.
Front Child Adolesc Psychiatry
November 2024
Applied Research & Evaluation, Child and Parent Resource Institute, Ministry of Children, Community and Social Services, London, ON, Canada.
Introduction: Psychotropic medication can be effective at stabilizing emotional and behavioural disturbances associated with physiological processes in children and youth. When medication benefits, indication or adverse effects are queried, deprescribing should be considered. Current guidelines for deprescribing are mainly for adults/elderly and largely theoretical, not practical, especially for polypharmacy.
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