A total of 33 patients with brain tumors and 22 patients with temporal epilepsy were compared. The differential diagnostic signs at the initial stages were revealed. In tumors, the disease starts most commonly from paroxysms of the isolated aura or complex absence epilepsy types. At the disease onset, the olfactory auras were recorded 6 times more frequently than in temporal epilepsy. The gustatory and vestibular auras also turned out more typical for epileptic onset . The psychomotor, psycho-sensory , ideational, and emotional paroxysmal manifestations were found to predominate at the onset of temporal epilepsy. As compared to epilepsy, the tumorous process leads much more swiftly to the development of pleomorphism and aggravation of the seizures, progress of the neurological symptomatology. The aggravated pre-epileptic anamnesis and hereditary as well as typical pointed wave epileptic activity on the EEG were demonstrable much more rarely in tumors.
Download full-text PDF |
Source |
---|
J Clin Med
January 2025
Department of Epileptology, University Hospital Bonn (UKB), 53127 Bonn, Germany.
In light of the growing interest in the bidirectional relationship between epilepsy and dementia, this review aims to provide an overview of the role of hyperphosphorylated tau (pTau) in cognition in human epilepsy. A literature search identified five relevant studies. All of them examined pTau burden in surgical biopsy specimens from patients with temporal lobe epilepsy.
View Article and Find Full Text PDFRINCH (Rhythmic Ictal Non-Clonic Hand movements), a lateralizing sign in frontotemporal epilepsy, has been well described in the adult epilepsy population but not in the pediatric setting. We looked for evidence of RINCH as an ictal sign in pediatric epilepsy monitoring unit reports in a large academic pediatric hospital. We found nine patients with RINCH ictal phenomenon over a five-year period.
View Article and Find Full Text PDFJ Neurosurg
January 2025
Departments of1Biomedical Engineering.
Objective: Epilepsy is a common neurological disease affecting nearly 1% of the global population, and temporal lobe epilepsy (TLE) is the most common type. Patients experience recurrent seizures and chronic cognitive deficits that can impact their quality of life, ability to work, and independence. These cognitive deficits often extend beyond the temporal lobe and are not well understood.
View Article and Find Full Text PDFJ Neurosurg
January 2025
1Service de Neurochirurgie, Université de Lorraine, CHRU-Nancy.
Objective: Recent voxel-based lesion symptom mapping (VLSM) studies have identified a critical region for picture naming, located 3.4 to 6.1 cm from the temporal pole.
View Article and Find Full Text PDFBrain
January 2025
Department of Biomedical Engineering, Vanderbilt University, Nashville, TN 37240, USA.
Resective epilepsy surgery can be an effective treatment for patients with medication-resistant focal epilepsy. Epilepsy resection consists of the surgical removal of an epileptic focus to stop seizure generation and disrupt the epileptic network. However, even focal surgical resections for epilepsy lead to widespread brain network changes.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!