A new option for volumetric restoration: poly-L-lactic acid.

J Eur Acad Dermatol Venereol

St Louis Hospital, Paris, France.

Published: May 2006

Objectives: The market for products and techniques that correct the visible signs of facial ageing is now huge. There is a diversity of devices and treatments now vying for a share of this growing marketplace, including polymer implants and injectable preparations that are based on an array of substances. The vast majority of these devices can only provide temporary correction of superficial lines and wrinkles, with volumetric augmentation being beyond their capabilities. The products and procedures suitable for the restoration of facial volume are discussed here.

Results: The restoration of facial volume has long been neglected in cosmetic rejuvenation as surgical procedures increase skin tension but do nothing to restore the underlying facial volume, which is a subtle yet important characteristic of the youthful face. Fortunately, devices are now available which can augment facial volume for long periods of time or even permanently. These include implants based on expanded polytetrafluoroethylene and silicone rubber, which provide permanent restoration of volume, but require invasive surgery and do not age with the surrounding tissues eventually resulting in an unnatural appearance. The cosmetic rejuvenation market now abounds with various injectable devices, including: poly-L-lactic acid (PLLA), polymethylmethacrylate, collagens, hyaluronic acids, silicone and calcium hydroxylapatite. The choice of which one to use in practice is physician led, based on facial assessments, product characteristics and the desires of the patient.

Conclusion: Although there is a wealth of products available, injectable PLLA (Sculptra) can restore volume to the face providing a natural look. Not only are the results of volume augmentation using this device long lasting, but they are also safe.

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1468-3083.2006.01517.xDOI Listing

Publication Analysis

Top Keywords

facial volume
16
poly-l-lactic acid
8
restoration facial
8
volume long
8
cosmetic rejuvenation
8
volume
7
facial
6
option volumetric
4
restoration
4
volumetric restoration
4

Similar Publications

Background And Aims: Benign ovarian neoplasms are common in the pediatric population. In young adult women, oophorectomy has been shown to negatively impact long-term ovarian endocrine function. Recently, ovarian-sparing surgery (OSS) has been proposed as it offers similar results to oophorectomy in terms of recurrence rates.

View Article and Find Full Text PDF

Biomarkers.

Alzheimers Dement

December 2024

Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.

Background: Stronger default mode (DMN) and bilateral frontoparietal control network (FPCN) resting-state functional connectivity are associated with reduced β-amyloid (Aβ)-related cognitive decline in cognitively unimpaired older adults, who were predominantly Aβ negative. This suggests that these networks might support cognitive resilience in the face of early AD pathology but it remains unclear whether these effects are apparent in preclinical AD. We investigated whether left-FPCN, right-FPCN, and DMN connectivity moderated the effect of Aβ on cognitive decline using a large multi-site dataset from the Anti-Amyloid Treatment in Asymptomatic Alzheimer's Disease (A4) study.

View Article and Find Full Text PDF

Biomarkers.

Alzheimers Dement

December 2024

Cognitive Impairment Diagnosis and Dementia Prevention Unit, Peruvian Institute of Neurosciences, Lima, Lima, Peru.

Background: The worldwide prevalence of Alzheimer's Disease (AD) surpasses 55 million, with Latin America reaching 11%, driven by demographic changes. Precise diagnosis necessitates neuroimaging, particularly magnetic resonance imaging (MRI). However, low- to middle-income countries face challenges in MRI accessibility due to limited imaging equipment and a shortage of specialized healthcare professionals trained in neuroimaging.

View Article and Find Full Text PDF

Background: Cognitive reserve (CR) is a property of the brain trait that allows for better-than-expected cognitive performance, relative to the degree of brain change over the life course. However, the neurophysiological markers of CR require further investigation. Electroencephalography (EEG) may provide an appropriate neurophysiological marker of CR.

View Article and Find Full Text PDF

Background: Right temporal variant frontotemporal dementia (rtvFTD), a new recognized entity among the FTD-spectrum, is characterized by right anterior temporal lobe (rATL) atrophy and a peculiar clinical presentation, involving face and emotions recognition, memory, and naming deficits and behavioral disturbances. Clinical diagnosis is challenging, since rtvFTD shares features with both the behavioral variant FTD (bvFTD) and the semantic variant primary progressive aphasia (svPPA), and there is no consensus yet on its designation and characterization. Although rATL neurodegeneration is a hallmark of this syndrome, only a few studies investigated patterns of gray matter (GM) atrophy.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!