Determination of the synthetic origin of methamphetamine samples by 2H NMR spectroscopy.

Anal Chem

Dipartimento di Chimica, Materiali, Ingegneria Chimica, Politecnico di Milano, and Istituto CNR per la Chimica del Riconoscimento Molecolare, Via Mancinelli 7, I-20131 Milano, Italy.

Published: May 2006

Samples of methamphetamine, prepared according to the most common synthetic pathways, were submitted to natural-abundance 2H NMR spectroscopy. The deuterium content at the various sites of the molecule was found to depend on its synthetic history. The technique provides a chemical fingerprint of methamphetamine samples and can give hints to trace back the starting materials and the synthetic procedures.

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http://dx.doi.org/10.1021/ac052105wDOI Listing

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