All 238 Clostridium difficile isolates were susceptible to metronidazole and vancomycin, whereas 84% and 1% were resistant to clindamycin and fusidic acid. Etest MICs for metronidazole were lower than agar dilution MICs (P < 0.01) but without difference in susceptible-intermediate-resistant categorization. No particular PCR ribotype was associated with clindamycin or fusidic acid resistance.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1472208PMC
http://dx.doi.org/10.1128/AAC.50.5.1890-1892.2006DOI Listing

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