Voriconazole penetrated well into the pulmonary epithelial lining fluid (ELF) in lung transplant patients receiving oral prophylaxis. The ELF concentrations exceeded those of the plasma, with an average ELF-to-plasma ratio of 11 (+/-8). A strong association between plasma and ELF concentrations (r(2) = 0.95) was noted.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1472209 | PMC |
| http://dx.doi.org/10.1128/AAC.50.5.1878-1880.2006 | DOI Listing |
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