AI Article Synopsis

  • Gastroparesis significantly impacts diabetic patients, leading to symptoms like nausea, early fullness, and weight loss, which can result in malnutrition and complications.
  • For those who don't respond to dietary changes and medication, gastric electrical stimulation (GES) offers a promising treatment option.
  • Two patients with diabetic gastroparesis were initially unfit for kidney transplants due to malnutrition, but after GES implantation, they both successfully received kidney transplants within two years.

Article Abstract

Gastroparesis is a debilitating condition that affects a significant number of diabetic patients. Some of these patients have end-stage renal disease and are in need of kidney transplant. Symptoms of gastroparesis include: early satiety, pyrosis, epigastric pain, nausea and vomiting, which may lead to caloric and electrolyte deficiencies as well as significant weight loss. A viable option for diabetic gastroparesis patients who fail first line treatments consisting of dietary changes and gastric prokinetic medications is gastric electrical stimulator (GES) implantation. We present a 41-yr-old man and 35-yr-old woman with diabetic gastroparesis, who were initially deemed unacceptable candidates for renal transplantation because of marked malnourishment and a concern that they would not be able to tolerate immunosuppressant medications. In less than two yr following GES implantation, each patient underwent a successful kidney transplant.

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Source
http://dx.doi.org/10.1111/j.1399-0012.2005.00454.xDOI Listing

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