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Three cases of hemoglobin M disease in a family lineage: Case report and literature review.
Medicine (Baltimore)
January 2025
Department of Pediatric Hematology, Children's Medical Center, The First Hospital of Jilin University, Changchun, China.
Rationale: This study presents a case of hemoglobin M disease (HMD), a rare inherited disorder characterized by persistent cyanosis and hypoxemia, observed across 3 generations within a single family. The diagnosis of HMD poses significant challenges, particularly in asymptomatic individuals, due to its rarity and the subtlety of its symptoms. Notably, there is a scarcity of reports on methemoglobinemia in pediatric populations, which further complicates early detection and intervention.
View Article and Find Full Text PDFAssessing Active and Passive Glenohumeral Rotational Deficits in Professional Tennis Players: Use of Normative Values at 90° and 45° of Abduction to Make Decisions in Injury-Prevention Programs.
Sports (Basel)
December 2024
Facultat de Psicologia Ciències de l'Educació i l'Esport (FPCEE) Blanquerna, Universitat Ramon Llull, 08022 Barcelona, Spain.
(1) Background: Glenohumeral internal and external rotational range-of-movement deficits (GIRDs and GERDs) are some of the primary outcomes used to determine the risk of injury in overhead athletes, such as tennis players. Nevertheless, the current testing position does not consider the fact that most tennis actions are repeated at 45° of abduction, and actively. The aim of this study was to establish normative values of pathological GIRDs and GERDs in tennis players and to provide normative values for both the passive and active rotational range of motion of the glenohumeral joint at 90° and 45° of abduction.
View Article and Find Full Text PDFTreatment Outcomes in Spinal Tumors According to Patients' Perspectives: A Focus on Indeterminate Spinal Instability.
Curr Oncol
January 2025
Spine Unit, Department of Orthopaedic Surgery and Traumatology, Aarau Cantonal Hospital, 5001 Aarau, Switzerland.
The objective of this study was to analyze treatment approaches and outcomes according to patients' perspectives for patients with indeterminate spinal instability caused by neoplastic lesions. Data were collected from 31 patients with a total of 147 spinal neoplastic lesions, 29 of whom had lesions classified as indeterminate. These lesions were divided into two groups: the low indeterminate group (SINS 7-9) and the high indeterminate group (SINS 10-12).
View Article and Find Full Text PDFIs inferior oblique botulinum toxin injection an effective surgical simulator prior to inferior oblique myectomy? A 30-year retrospective review.
Strabismus
January 2025
Ophthalmology Department, Aintree University Hospital, Liverpool, UK.
Botulinum toxin A (BTX) injected into the inferior oblique muscle temporarily simulates the post-operative effect of an inferior oblique myectomy (IOM). This can aid in surgical planning, especially given the irreversible nature of IOM. This study evaluates the efficacy of BTX as a pre-operative simulator and compares its effects to those of IOM.
View Article and Find Full Text PDFPhase II Trial of Brain MRI Surveillance in Stage IV Breast Cancer.
Neuro Oncol
January 2025
Department of Breast Oncology, Moffitt Cancer Center.
Background: Screening of asymptomatic stage IV breast cancer with brain MRIs is currently not recommended by National Comprehensive Cancer Network (NCCN) Guidelines. The incidence of asymptomatic brain metastasis is not well documented.
Methods: The study is designed as a single arm, phase II trial, with the goal of investigating surveillance brain MRIs in neurologically asymptomatic patients with metastatic breast cancer.
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