AI Article Synopsis
- Solitary keratoacanthoma (KA) is a benign skin tumor known for its quick growth and potential to shrink on its own, with its causes and classification still debated.
- A study involving 78 KA patients and 199 controls aimed to examine the link between smoking and KA, revealing that a significantly higher percentage of KA patients were smokers (69.2%) compared to controls (21.6%).
- The adjusted odds ratio indicated a strong association between smoking and KA (9.1), but factors like tumor size and location were not statistically linked to smoking habits.
Article Abstract
Solitary keratoacanthoma (KA) is a common benign epithelial tumor of the skin characterized by rapid growth and a tendency toward spontaneous regression. The exact etiology and classification of KA are a matter of debate. Smokers also seem to be more affected than persons who never smoke. The objective of this study was to evaluate the association between solitary KA and smoking habit. A case-control study involving 78 patients diagnosed with KA and 199 controls from the related community was performed to evaluate the association between cigarette smoking and KA. A higher smoking prevalence was noted in cases (69.2 %) than controls (21.6 %) and the odds ratio adjusted for sex and age was 9.1 (95 % CI 4.9 to 17.1, p< 0.01). The mean tumoral diameter at surgery and the site of involvement was not statistically related to smoking. These findings suggest that cigarette smoking is associated with the development of KA.
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