The objective of the study was the determination of the ulcerorhaphy in perforated duodenal ulcers, a clinical course of the disease in the post-operational period and a delineation of the treatment tactics in the case of various morpho-functional abnormalities in the post-ulcerorhaphic period. To this effect, the method of retrospective analysis, allowing comparison of the pre- and post- operational pictures of the disease has been applied. As a result the post-closure syndromes of the perforated ulcer were detected in 42 (37,9%) patients. In the case of the presence of the syndrome, the disease is aggressive, emerging as a recurrent refractive ulcer and various severe complications. This kind of the disease is resistant to a conservative therapy, thus, requiring a drastic surgery.

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